Evidence map›Paper›PMID 41609423›Full record

ArticleBioinformatics (Oxford, England)2026

DNAvi: integration, statistics, and visualization of cell-free DNA fragment traces.

Anja Hess, Dominik Seelow, Helene Kretzmer

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anja HessExploratory Diagnostic Sciences, Center of Genomic Medicine, Berlin Institute of Health at Charité Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0001-6634-9502
Dominik SeelowExploratory Diagnostic Sciences, Center of Genomic Medicine, Berlin Institute of Health at Charité Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-9746-4412
Helene KretzmerMax Planck Institute for Molecular Genetics, 14195 Berlin, Germany.ORCID 0000-0002-0723-4980

Funding

Max Planck Society
6 · The paper itself

Abstract

summaryDNAvi is a Python-based tool for rapid grouped analysis and visualization of cell-free DNA fragment size profiles directly from electrophoresis data, overcoming the need for sequencing in basic fragmentomic screenings. It enables normalization, statistical comparison, and publication-ready plotting of multiple samples, supporting quality control and exploratory fragmentomics in clinical and research workflows. AVAILABILITY AND IMPLEMENTATION: DNAvi is implemented in Python and freely available on GitHub at https://github.com/anjahess/DNAvi under a GNU General Public License v3.0, along with source code, documentation, and examples. An archived version is available under https://doi.org/10.5281/zenodo.18401705.

Indexed as

Cell-Free Nucleic AcidsSoftwareSequence Analysis, DNACell-Free Nucleic Acids

Identifiers

PMID41609423
PMCPMC12904835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.