Evidence map›Paper›PMID 41609402›Full record

ArticleJNCI cancer spectrum2026

Emergency cancer diagnosis in older adults: patterns, subgroups, and implications for health-care quality metrics.

Sarah E Soppe, Sharon Peacock Hinton, Ellis C Dillon, Sandi L Pruitt, Georgios Lyratzopoulos, Matthew E Barclay, Megan A Mullins, Allison W Kurian, Nicholas Pettit, Matthew Thompson and 1 more

Abstract read
In one paragraph

Article in JNCI cancer spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah E SoppeDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0009-0000-2465-9377
Sharon Peacock HintonDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0001-6045-5283
Ellis C DillonCenter on Aging, University of Connecticut, Farmington, CT, United States.ORCID 0000-0001-9910-0869
Sandi L PruittDepartment of Social and Behavioral Sciences, Peter O'Donnell Jr School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, United States.ORCID 0000-0002-1007-9176
Georgios LyratzopoulosEpidemiology of Cancer Healthcare and Outcomes (ECHO), Department of Behavioural Science and Health, Institute of Epidemiology and Health Care (IECH), University College London, London, United Kingdom.ORCID 0000-0002-2873-7421
Matthew E BarclayEpidemiology of Cancer Healthcare and Outcomes (ECHO), Department of Behavioural Science and Health, Institute of Epidemiology and Health Care (IECH), University College London, London, United Kingdom.ORCID 0000-0003-1148-1922
Megan A MullinsHarold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, United States.ORCID 0000-0003-2753-9068
Allison W KurianDepartment of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, United States.ORCID 0000-0002-6175-9470
Nicholas PettitDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.ORCID 0000-0002-4457-591X
Matthew ThompsonDepartment of Family Medicine, University of Washington, Seattle, WA, United States.
Caroline A ThompsonDepartment of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID 0000-0001-9990-9756

Funding

Diagnosis of Cancer in the Emergency Room - Explaining Persistent Disparities - Diversity SupplementR01CA264176 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI THOMPSON, CAROLINE AVERY · 2021 to 2025
$2.0M
Cancer Research United Kingdom C18081/A18180National Cancer Institute at the National Institutes of Health R01-CA-264176NCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INCI NIH HHS R01 CA264176
6 · The paper itself

Abstract

backgroundCancer diagnosis originating in emergency departments (emergency presentation) contributes to poorer cancer survival and reflects aggressive disease and limited access to routine health care. This study characterized emergency presentations for a range of cancers and subclassified by whether patients were hospitalized after the emergency encounter, with the hypothesis that, compared with those hospitalized, patients not requiring hospitalization more specifically represent barriers to timely and adequate care.

methodsWe analyzed Surveillance, Epidemiology, and End Results-Medicare data for patients aged 66 years and older diagnosed with 14 cancer types (2008-2017; n = 614 885). We described emergency presentation overall and demographic and clinical characteristics across subgroups using linear regression and assessed differences in health-care utilization before the emergency presentation classification window.

resultsIn total, 234 606 (38%) patients were classified as emergency presentations, with 187 439 (80%) hospitalized. Emergency presentations were more likely than nonemergency presentations to have prediagnostic emergency care (40%, 95% confidence interval [CI] = 40% to 40%) vs 30% (95% CI = 29% to 30%) and less likely to have nonemergency care for potential cancer symptoms (61%, 95% CI = 61% to 61%, vs 67%, 95% CI = 67% to 67%), with minimal variation between inpatient and outpatient emergency presentations. Compared with inpatient emergency presentations, outpatient emergency presentations were more often younger than 70 years old (24%, 95% CI = 23% to 24%, vs 19%, 95% CI = 19% to 19%), nonmetropolitan residents (25%, 95% CI = 24% to 25%, vs 12%, 95% CI = 12% to 12%), and had localized cancer (25%, 95% CI = 25% to 26%, vs 17%, 95% CI = 17% to 17%).

conclusionsMore than one-third of older adult US cancer patients with these cancer types are diagnosed through emergency presentation, with most requiring hospitalization. Outpatient emergency presentations are more common among patients in rural areas with less advanced cancers, suggesting they may be an informative indicator of avoidable barriers to care less influenced by underlying health status.

Indexed as

Emergency Service, HospitalHospitalizationNeoplasmsQuality Indicators, Health CareAgedAged, 80 and overAge FactorsEmergency Room VisitsFemaleHumansLinear ModelsMaleMedicareSEER ProgramUnited States

Identifiers

PMID41609402
PMCPMC12953026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.