High Prevalence and Genotypic Diversity of Persistent Chlamydia Trachomatis Infections Among South African Adolescent Girls and Young Women: A Tale of Two Cities.
Article in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
17 authors.
Smritee DabeeDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-8373-9593
Shaun BarnabasDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-4819-9501
Bart VersteegKnowledge Institute of the Dutch Association of Medical Specialists, Rijksinstituut voor Volksgezondheid en Milieu (RIVM), Bilthoven, Netherlands.ORCID 0000-0003-2606-8057
Brian KullinDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-5460-1977
Shameem Z JaumdallyDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-0316-7087
Hoyam GamieldienDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-8352-9705
Nonhlanhla MkhizeCentre for HIV and STIs, National Health Laboratory Service, National Institute for Communicable Disease, Johannesburg, South Africa.ORCID 0000-0003-3037-1243
Etienne MullerCentre for HIV and STIs, National Health Laboratory Service, National Institute for Communicable Disease, Johannesburg, South Africa.ORCID 0000-0003-1802-0272
Venessa MasekoCentre for HIV and STIs, National Health Laboratory Service, National Institute for Communicable Disease, Johannesburg, South Africa.ORCID 0000-0002-9707-9485
Katherine GillDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.
Darren P MartinDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-8785-0870
Glenda GrayFaculty of Health Sciences, Perinatal HIV Research Unit, University of the Witwatersrand, Diepkloof, Johannesburg, South Africa.ORCID 0000-0002-9510-5774
Linda-Gail BekkerDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-0755-4386
David A LewisWestern Sydney Sexual Health Centre, Western Sydney Local Health District, Parramatta, New South Wales, Australia.
Heather B JaspanDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-0745-6073
Sylvia M BruistenDepartment of Infectious Diseases, Public Health Service Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0003-4897-4261
Jo-Ann S PassmoreDivision of Medical Virology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.ORCID 0009-0002-3151-3514
Funding
EDCTP Strategic Primer 2011.41304.038South African Medical Research Council
6 · The paper itself
Abstract
Chlamydia trachomatis (CT) is the most common sexually transmitted bacterial infection globally, significantly affecting adolescent girls and young women (AGYW) in South Africa. This study investigated CT prevalence and genotypic diversity among 298 AGYW from Cape Town and Johannesburg, revealing an overall prevalence of 29.5%. Prevalence was higher in Cape Town (41.6%) compared to Johannesburg (17.4%; P < .0001). Genetic analysis identified 34 sequence types, including 15 novel variants. Longitudinal data highlighted frequent reinfections or persistent infections despite treatment. These findings underscore the importance of addressing CT's genetic diversity for improved reproductive health strategies and vaccine development.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
High Prevalence and Genotypic Diversity of Persistent Chlamydia Trachomatis Infections Among South African Adolescent Girls and Young Women: A Tale of Two Cities. · full record | OpenQuestion