Evidence map›Paper›PMID 41609262›Full record

ArticleJACC. Case reports2026

Caseous Calcification of the Mitral Annulus With Aortic Root Fistula and Pseudoaneurysm: Multimodality Imaging-Guided Repair.

M Mercedes Crestanello, Kyle W Klarich, Thomas A Foley, Sorin V Pislaru, Gabor Bagameri

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M Mercedes CrestanelloDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Kyle W KlarichDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Thomas A FoleyDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Diagnostic Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Sorin V PislaruDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Gabor BagameriDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota, USA. Electronic address: bagameri.gabor@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaseous calcification of the mitral annulus (CCMA) fistulizing into the aortic root has not been described. CASE SUMMARY: A 66-year-old man with severe regurgitation from mitral valve prolapse presented with a calcified mass extending from the anterolateral trigone of the mitral valve to the anterolateral papillary muscle. Multimodality imaging revealed a pseudoaneurysm in the anterolateral trigone communicating with the aortic root without aortic valve dysfunction. A 3-dimensional (3D) printed model delineated anatomy and supported valve repair, fistula closure, and aortic valve preservation. DISCUSSION: This novel case of CCMA with pseudoaneurysm fistulizing into the aortic root demonstrated how multimodality imaging and 3D modeling facilitate valve-sparing repair. TAKE-HOME MESSAGES: Fistulization of CCMA into the aortic root is exceptionally rare. Multimodality imaging and 3D modeling enabled precise anatomic characterization, mitral valve repair, and closure of the fistulous tract. Advanced imaging can expand surgical options and support preservation of native valves in anatomically complex diseases.

Indexed as

aortic valvemitral valvepapillary musclesregurgitationvalve repair

Identifiers

PMID41609262
PMCPMC12882678

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.