Evidence map›Paper›PMID 41608744›Full record

ArticleFrontiers in physiology2025

Clinical application of capsule endoscopy in children with small bowel disease in Wuhan, China.

Pingping Xu, Dan Luo, Baoxiang Wang, Yingru Liu, Siyue Tang, Shan Guo, Zhi Yu, Leyong Zheng, Jie Feng, Huifen Huang and 3 more

Abstract read
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Pingping Xu *Department of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Dan Luo *Department of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Baoxiang WangDepartment of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Yingru LiuMedical Department of School of Medicine, Wuhan University of Science and Technology, Wuhan, China.
Siyue TangMedical Department of School of Medicine, Wuhan University of Science and Technology, Wuhan, China.
Shan GuoDepartment of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Zhi YuDepartment of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Leyong ZhengDepartment of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Jie FengDepartment of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Huifen HuangDepartment of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Yuan GaoDepartment of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.
Fang WangHealth Management College of Xianning Vocational and Technical College, Xianning, China.
Wei SuDepartment of Gastroenterology/Center of Digestive Endoscopy of Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technolog, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the clinical application value of capsule endoscopy (CE) in the diagnosis of small intestinal diseases in children in Wuhan. Methods: A retrospective analysis was conducted on the clinical data of children who underwent CE examination at the Digestive Endoscopy Center of Wuhan Children's Hospital from July 2021 to November 2024. The completion rate of CE examination, disease detection rate, small intestinal transit time, and adverse reactions were analyzed. Results: Among the 151 children, 97 were male (64.24%) and 54 were female (35.76%), with an average age of 10.9 years. CE was swallowed orally in 133 cases (88.08%) and placed through gastroscopy in 18 cases (11.92%). Complete small intestinal examination was achieved in 144 cases (95.36%), with an average small intestinal transit time of 4 h and 11 min for those swallowed orally and 4 h and 16 min for those placed through gastroscopy. Seven cases (4.64%) did not complete the full small intestinal examination. Abdominal pain (99 cases, 65.56%), anemia (19 cases, 12.58%), and hematochezia and melena (23 cases, 15.23%) were the most common indications for examination. Among the 151 children, 116 (76.82%) had positive results, including 68 cases of nonspecific small intestinal inflammation, 29 cases of Crohn's disease, 4 cases of Henoch-Schönlein purpura, 6 cases of Meckel's diverticulum, 4 cases of small intestinal parasitic disease, 2 cases of collagenous gastritis, 1 case of melanocytic polyp, 1 case of lymphangiectasia, and 1 case of blue rubber bleb nevus syndrome. Nonspecific small intestinal inflammation was the most common in all age groups, while Crohn's disease was mainly seen in the 7-12 years and 13-18 years age groups, accounting for 55.17% and 44.83%, respectively. No adverse reactions occurred in all children. Conclusion: CE examination in children in Wuhan has a high disease detection rate and good safety. CE can be further promoted in the diagnosis of small intestinal diseases in children.

Indexed as

capsule endoscopychildrenclinical applicationpediatric CEsmall intestinal diseases

Identifiers

PMID41608744
PMCPMC12834712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.