Evidence map›Paper›PMID 41608723›Full record

ArticleStroke (Hoboken, N.J.)2025

Effect of Time from Puncture to Recanalization on Poststroke Disposition and Associated Costs.

Akash Agrawal, Arjun Agrawal, Jase Howell, Sevin Barringer-Hoonhout, James Fleck, Jason Mackey, Andrew DeNardo, Daniel Gibson, Krishna Amuluru, Yasir Saleem and 5 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Akash AgrawalDepartment of Neurological Surgery Goodman Campbell Brain and Spine Carmel IN USA.
Arjun AgrawalDepartment of Neurological Surgery Goodman Campbell Brain and Spine Carmel IN USA.ORCID https://orcid.org/0009-0002-1395-9344
Jase HowellDepartment of Neurological Surgery Goodman Campbell Brain and Spine Carmel IN USA.
Sevin Barringer-HoonhoutDepartment of Neurological Surgery Goodman Campbell Brain and Spine Carmel IN USA.
James FleckDepartment of Neurology Indiana University School of Medicine Indianapolis IN USA.
Jason MackeyDepartment of Neurology Indiana University Indianapolis IN USA.ORCID https://orcid.org/0000-0002-6867-8630
Andrew DeNardoDepartment of Neurology Indiana University Indianapolis IN USA.
Daniel GibsonDepartment of Interventional Neuroradiology Goodman Campbell Brain and Spine Institute Carmel IN USA.ORCID https://orcid.org/0009-0003-9457-4004
Krishna AmuluruAscension St. Vincent Medical Center Goodman Campbell Brain and Spine Carmel IN USA.ORCID https://orcid.org/0000-0002-8859-8574
Yasir SaleemDepartment of Neurology Saint Francis Hospital Tulsa OK USA.
Charles KulwinAscension St. Vincent Medical Center Goodman Campbell Brain and Spine Carmel IN USA.ORCID https://orcid.org/0000-0001-9990-2028
Troy PaynerAscension St. Vincent Medical Center Goodman Campbell Brain and Spine Carmel IN USA.ORCID https://orcid.org/0000-0002-8799-679X
Kushal ShahDepartment of Neurological Surgery Goodman Campbell Brain and Spine Carmel IN USA.
J MoccoDepartment of Neurosurgery Mount Sinai Hospital New York NY USA.
Daniel SahleinDepartment of Neurological Surgery Goodman Campbell Brain and Spine Carmel IN USA.ORCID https://orcid.org/0000-0002-6591-9427

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigates the relationship between procedure time during stroke thrombectomy and acute posthospital disposition, as well as the associated costs. Despite extensive literature focusing on long-term outcomes, immediate posthospital patient disposition and its economic impact remain underexplored.

methodsThis retrospective study analyzed 721 patients undergoing thrombectomy at a single neuroendovascular practice from 2011 to 2020. Key metrics included disposition and time from groin puncture to recanalization (PTR). Patient dispositions were categorized into 4 groups: acute/subacute rehabilitation, home/home with physical therapy (PT), death/hospice, and long-term care. Multinomial logistic regression, adjusted for age, National Institutes of Health Stroke Scale score, and comorbidities, was used to model predicted disposition probabilities over a range of PTR times. Disposition-based direct acute care costs were applied to estimate the cost impact of PTR delays.

resultsPTR was significantly associated with disposition (

conclusionLonger PTR is associated with increased death/hospice dispositions and measurable cost increases. Extrapolating nationally, every 15-minute PTR delay results in a $7.2-$7.7 million annual increase in stroke-related health care costs.

Indexed as

acute outcomepuncture to recanalizationstrokethrombectomy

Identifiers

PMID41608723
PMCPMC12697650

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.