Evidence map›Paper›PMID 41608698›Full record

ReviewStroke (Hoboken, N.J.)2025

Consensus Statement on Middle Meningeal Artery Embolization in Chronic Subdural Hematoma Treatment: A Guideline from the Society of Vascular and Interventional Neurology Guidelines and Practice Standards Committee.

Farhan Siddiq, Muhammad Shakir, Thanh N Nguyen, Ameer E Hassan, Mohamad Abdalkader, Cynthia L Kenmuir, David S Liebeskind, Robin Novakovic, Shahram Majidi, Sunil A Sheth and 4 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Stroke (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07751887 (Prospective Multicentric Study of Middle Meningeal Artery Embolisation Combined With Surgical Treatment for Chronic Subdural Hematoma), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07751887 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Prospective Multicentric Study of Middle Meningeal Artery Embolisation Combined With Surgical Treatment for Chronic Subdural Hematoma

TypeinterventionalSponsorUniversity Hospital Hradec KraloveRan2026 to 2029Enrolled200ConditionsChronic Subdural HematomaArmsMiddle Meningeal Artery Embolisation
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Farhan SiddiqDepartment of Neurosurgery University of Missouri, 1 Hospital Drive Columbia MO.ORCID https://orcid.org/0000-0001-8568-1543
Muhammad ShakirDepartment of Neurosurgery University of Missouri, 1 Hospital Drive Columbia MO.
Thanh N NguyenBoston Medical Center Boston University School of Medicine Boston MA.
Ameer E HassanDepartment of Neuroscience Valley Baptist Medical Center Harlingen TX.
Mohamad AbdalkaderBoston Medical Center Boston University School of Medicine Boston MA.
Cynthia L KenmuirDepartment of Neurology University of Pittsburgh Medical Center Altoona PA.
David S LiebeskindDepartment of Neurology Neurovascular Imaging Research Core, UCLA Los Angeles CA.
Robin NovakovicDepartment of Neurology and Radiology UT Southwestern Dallas TX.
Shahram MajidiDepartment of Neurosurgery Icahn School of Medicine at Mount Sinai New York NY USA.
Sunil A ShethDepartment of Neurology, McGovern Medical School UTHealth Houston TX.
Mohammad El-GhanemNeuroendovascular Surgery HCA Houston Northwest/University of Houston College of Medicine Houston TX.
Santiago Ortega-GutierrezDepartment of Neurology, Neurosurgery & Radiology University of Iowa Hospitals and Clinics Iowa City IA.
Waldo R GuerreroDepartment of Neurology and Brain Repair University of South Florida Tampa FL.
Amer M MalikDepartment of Neurology University of Miami Miller School of Medicine Miami FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmerging evidence from observational studies, meta-analyses, and clinical trials has reshaped the treatment landscape of chronic subdural hematoma (CSDH). This guideline provides updated recommendations on diagnosis, patient selection, and medical, surgical, and endovascular management.

methodsThe Society of Vascular and Interventional Neurology Guidelines and Practice Standards committee formed a writing group of interdisciplinary experts to review current literature. Recommendations were based on clinical trial data, observational studies, and expert consensus, following the Society of Vascular and Interventional Neurology Class of Recommendation and Level of Evidence framework.

resultsEMBOLISE (Embolization of the Middle Meningeal Artery With ONYX Liquid Embolic System for Subacute and Chronic Subdural Hematoma), STEM (SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma), MAGIC-MT (Managing Non-acute Subdural Hematoma Using Liquid Materials: A Chinese Randomized Trial of MMA Treatment), and MEMBRANE (Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL n-butyl cyanoacrylate) trials highlight the efficacy and safety of middle meningeal artery embolization (MMAE) in CSDH. EMBOLISE (n = 400; MMAE with surgery, n = 197; surgery alone, n = 203) showed that MMAE plus surgery reduced 90-day hematoma recurrence to 4.1% versus 11.3% with surgery alone (relative risk = 0.36; 95% CI = 0.11-0.80;

conclusionsThese results suggest that MMAE plus standard treatment of CSDH shows promising results and may become a standard of care for managing CSDH in selected patients. These guidelines provide evidence-based recommendations for the diagnosis, patient selection, and treatment of CSDH.

Indexed as

chronic subdural hematomaconsensus statementCSDHmanagement guidelinesneurointerventionpractice standardstreatment recommendations

Identifiers

PMID41608698
PMCPMC12697622

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.