From image to action: Evaluating the translation of coronary CT angiography findings into cardiovascular prevention in the emergency department.

Background: Coronary CT angiography (CCTA) is increasingly used in emergency departments (ED) for chest pain evaluation, but its role in directing preventive therapy at discharge remains unclear. Objectives: We aimed to determine whether CCTA findings were associated with statin initiation at discharge and to identify gaps in preventive care. Methods: We conducted a retrospective observational study of adult patients (≥18 years) undergoing CCTA for chest pain in the ED of a large academic hospital. CCTA findings were categorized as no CAD, non-obstructive CAD (<50% stenosis), or obstructive CAD (≥50% stenosis). The primary outcome was statin initiation at discharge among statin-naïve patients. Secondary outcomes included cardiology referral and heart disease education. We applied multivariable Firth logistic regression for the primary outcome and modified Poisson regression with robust variance for secondary outcomes. Results: Of 1410 participants (mean age=53.5 ± 10.9 years; 52.8% female), 723 (51.3%) had no CAD and 687 (48.7%) had CAD (69.3% non-obstructive, 30.7% obstructive). In statin-naïve patients ( Conclusions: CCTA findings strongly predict statin initiation at discharge, yet large treatment gaps persist, especially in non-obstructive CAD. Routine ED CCTA provides a missed but actionable opportunity to initiate guideline-based therapy and reduce ASCVD burden.