Evidence map›Paper›PMID 41608637›Full record

ArticleInternational journal of biological sciences2026

Nicotinamide N-Methyl Transferase (NNMT) Sustains Innate Sensitivity to NAMPT Inhibition in YAP-dependent Stem-like/Mesenchymal Prostate Cancer.

Ágata Sofia Assunção Carreira, Marianna Ciuffreda, Nathakan Thongon, Charles M Haughey, Adam Pickard, Sharon L Eddie, Rebecca E Steele, Elena Cerri, Romina Belli, Daniele Peroni and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ágata Sofia Assunção CarreiraUniversity of Trento, CIBIO - Laboratory of Genomic Screening, Trento, Italy.
Marianna CiuffredaUniversity of Trento, CIBIO - Laboratory of RNA and Disease Data Science, Trento, Italy.
Nathakan ThongonUniversity of Trento, CIBIO - Laboratory of Genomic Screening, Trento, Italy.
Charles M HaugheyPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Adam PickardPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Sharon L EddiePatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Rebecca E SteelePatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Elena CerriUniversity of Trento, CIBIO - Laboratory of Genomic Screening, Trento, Italy.
Romina BelliUniversity of Trento, CIBIO - Mass Spectrometry and Proteomics Facility, Trento, Italy.
Daniele PeroniUniversity of Trento, CIBIO - Mass Spectrometry and Proteomics Facility, Trento, Italy.
Elisa FacenUniversity of Trento, CIBIO - Laboratory of Genomic Screening, Trento, Italy.
Irene CaffaDepartment of Internal Medicine and Medical Specialties (DIMI), University of Genoa, 16132 Genoa, Italy.
Moustafa GhanemDepartment of Internal Medicine and Medical Specialties (DIMI), University of Genoa, 16132 Genoa, Italy.
Alessio NencioniDepartment of Internal Medicine and Medical Specialties (DIMI), University of Genoa, 16132 Genoa, Italy.
Andrea LunardiUniversity of Trento, CIBIO - Laboratory of Genomic Screening, Trento, Italy.
Toma TebaldiUniversity of Trento, CIBIO - Laboratory of RNA and Disease Data Science, Trento, Italy.
Ian G MillsPatrick G Johnston Centre for Cancer Research, Queen's University, Belfast BT9 7AE, UK.
Alessandro ProvenzaniUniversity of Trento, CIBIO - Laboratory of Genomic Screening, Trento, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the NAD

Indexed as

CytokinesNicotinamide N-MethyltransferaseNicotinamide PhosphoribosyltransferaseProstatic NeoplasmsProstatic Neoplasms, Castration-ResistantAcrylamidesAdaptor Proteins, Signal TransducingAnimalsCell Line, TumorHumansMaleMiceNeoplastic Stem CellsPiperidinesTranscription FactorsYAP-Signaling ProteinsAcrylamidesAdaptor Proteins, Signal TransducingCytokinesN-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamideNicotinamide N-MethyltransferaseNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humanNNMT protein, humanPiperidinesTranscription FactorsYAP1 protein, humanYAP-Signaling ProteinsCRPCEMTFK866NAMPTNNMTStemnessYAP

Identifiers

PMID41608637
PMCPMC12836488

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.