Evidence map›Paper›PMID 41608602›Full record

ArticleWorld journal of clinical cases2026

Diagnostic perspectives on mixed connective tissue disease with tuberculosis overlap.

Shree V Dhotre, Pradnya S Dhotre, Ajay M Gavkare, Basavraj S Nagoba

Abstract readLetter
In one paragraph

Article in World journal of clinical cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shree V DhotreDepartment of Microbiology, Ashwini Rural Medical College, Hospital and Research Centre, Solapur 413006, Maharashtra, India.
Pradnya S DhotreDepartment of Biochemistry, Ashwini Rural Medical College, Hospital and Research Centre, Solapur 413006, Maharashtra, India.
Ajay M GavkareDepartment of Physiology, Government Medical College, Buldhana 443001, Maharashtra, India.
Basavraj S NagobaDepartment of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Latur 413531, Maharashtra, India. dr_bsnagoba@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recently published case report describing mixed connective tissue disease coexisting with tuberculosis (TB) provides an important contribution to the growing literature on complex autoimmune-infectious disease interactions. This letter expands on the diagnostic challenges highlighted by the authors by defining its added clinical value: Identifying practical diagnostic "red flags", emphasizing parallel consideration of autoimmunity and infection, and proposing a pragmatic approach to evaluation in TB-endemic settings. Early immunological testing, differentiated pulmonary assessment, and multidisciplinary decision-making are essential when overlapping features obscure timely diagnosis and complicate therapeutic choices.

Indexed as

Autoimmune diseaseDiagnostic red flagsImmunosuppressionMixed connective tissue diseaseTuberculosis

Identifiers

PMID41608602
PMCPMC12836073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.