Evidence map›Paper›PMID 41608565›Full record

ArticleTheranostics2026

The novel B-cell epitope peptide vaccine, MAX449, exhibits significant anti-tumor efficacy and enhances the therapeutic effects of PD-1 antibodies on tumors by modulating the activity of PMN-MDSCs.

Hong Yang, Xiao Han, Boshao Deng, Yunpei Zhao, Jing Zhao, Yufei Wu, Guokang Liu, Shiyu Zeng, Siyi Wang, Zhejuan Shen and 5 more

Abstract read
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hong YangDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Xiao HanDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Boshao DengDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Yunpei ZhaoDepartment of Pharmacy, Southwest Hospital, Third Military Medical University, Chongqing, China.
Jing ZhaoBiomedical Analysis Center, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Yufei WuDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Guokang LiuDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Shiyu ZengDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Siyi WangDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Zhejuan ShenDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Lulu WangDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Zihan SunDepartment of breast and thyroid Guiqian international general hospital, Guiyang 550000, China.
Wenping LuFaculty of Hepato-Pancreato-Biliary Surgery, First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Yuzhang WuDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Jian ChenDepartment of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cancer VaccinesEpitopes, B-LymphocyteMyeloid-Derived Suppressor CellsNeoplasmsProgrammed Cell Death 1 ReceptorAnimalsCell Line, TumorComplement C5aFemaleHumansMiceMice, Inbred BALB CMice, Inbred C57BLProtein Subunit VaccinesSignal TransductionVaccines, SubunitCancer VaccinesComplement C5aEpitopes, B-LymphocyteProgrammed Cell Death 1 ReceptorProtein Subunit VaccinesVaccines, SubunitB-cell epitope peptide vaccineC5a-C5aR pathwayMAX449PD-1 antibodytumor immunotherapy

Identifiers

PMID41608565
PMCPMC12846753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.