Evidence map›Paper›PMID 41608552›Full record

ArticleJournal of surgical case reports2026

Case series: oncologic patients in remission with giant ventral hernia treated with botulinum toxin and component separation.

Luis Muñoz-Andrade, Francisco Nevárez, Sandra Chalén, Yanalín Mantuano

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luis Muñoz-AndradeDepartment of Oncology Surgery, National Oncology Institute SOLCA Guayaquil, Guayaquil, 090505, Ecuador.ORCID https://orcid.org/0000-0002-9682-5896
Francisco NevárezDepartment of Digestive Surgery, National Oncology Institute SOLCA Guayaquil, Av. Pedro Menéndez Gilbert, Guayaquil, Guayas 090505, Ecuador.ORCID https://orcid.org/0000-0002-5879-9711
Sandra ChalénDepartment of Plastic Surgery, National Oncology Institute SOLCA Guayaquil, Av. Pedro Menéndez Gilbert, Guayaquil, Guayas 090505, Ecuador.ORCID https://orcid.org/0000-0002-9875-0293
Yanalín MantuanoDepartment of Plastic Surgery, National Oncology Institute SOLCA Guayaquil, Av. Pedro Menéndez Gilbert, Guayaquil, Guayas 090505, Ecuador.ORCID https://orcid.org/0000-0001-9824-1272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant ventral hernia represents a surgical challenge, particularly in oncologic patients in remission, due to large fascial defects and loss of domain. Botulinum toxin has been incorporated as an adjuvant to facilitate fascial closure through chemical relaxation of the abdominal wall. We describe four oncologic patients in remission with giant ventral hernia treated with preoperative botulinum toxin and repair using component separation with retromuscular polypropylene mesh placement. The procedures were performed without intraoperative complications or early recurrence. The technique allowed tension-free fascial closure with favorable postoperative outcomes. Botulinum toxin appears to be a useful and safe tool for the repair of complex ventral hernias in oncologic patients in remission, promoting fascial approximation and reducing the need for more invasive procedures.

Indexed as

abdominal wall reconstructionbotulinum toxincomponent separationloss of domainoncologyventral hernia

Identifiers

PMID41608552
PMCPMC12840580

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.