Evidence map›Paper›PMID 41608493›Full record

ArticleWorld journal of orthopedics2026

Coronal plane alignment of the knee phenotypes and ankle joint coronal plane alignment patterns in Egyptian population.

Ahmed A Khalifa, Mohamed Moustafa, Shikuria Lemma, Mostafa Fayez, Ahmed M Abdelaal, Amr A Fadle

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Article in World journal of orthopedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ahmed A KhalifaDepartment of Orthopaedics, Qena Faculty of Medicine and University Hospital, South Valley University, Qena 83523, Egypt. ahmed_adel0391@med.svu.edu.eg.
Mohamed MoustafaDepartment of Orthopedic Surgery and Traumatology, Assiut University Hospital, Assiut 71515, Egypt.
Shikuria LemmaDepartment of Orthopaedics, Black Lion Specialized Hospital, Addis Ababa 1165, Ethiopia.
Mostafa FayezDepartment of Orthopedic Surgery and Traumatology, Assiut University Hospital, Assiut 71515, Egypt.
Ahmed M AbdelaalDepartment of Orthopedic Surgery and Traumatology, Assiut University Hospital, Assiut 71515, Egypt.
Amr A FadleDepartment of Orthopedic Surgery and Traumatology, Assiut University Hospital, Assiut 71515, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn an era leaning toward a personalized alignment of total knee arthroplasty, coronal plane alignment of the knee (CPAK) phenotypes for each population are studied; furthermore, other possible variables affecting the alignment, such as ankle joint alignment, should be considered.

aimTo determine CPAK distribution in the North African (Egyptian) population with knee osteoarthritis and to assess ankle joint line orientation (AJLO) adaptations across different CPAK types.

methodsA cross-sectional study was conducted on patients with primary knee osteoarthritis and normal ankle joints. Radiographic parameters included the mechanical lateral distal femoral angle, medial proximal tibial angle, and the derived calculations of joint line obliquity (JLO) and arithmetic hip-knee-ankle angle (aHKA). The tibial plafond horizontal angle (TPHA) was used for AJLO assessment, where 0° is neutral (type N), < 0° is varus (type A), and > 0° is valgus (type B). The nine CPAK types were further divided into 27 subtypes after incorporating the three AJLO types.

resultsA total of 527 patients (1054 knees) were included for CPAK classification, and 435 patients (870 knees and ankles) for AJLO assessment. The mean age was 57.2 ± 7.8 years, with 79.5% females. Most knees (76.4%) demonstrated varus alignment (mean aHKA was -5.51° ± 4.84°) and apex distal JLO (55.3%) (mean JLO was 176.43° ± 4.53°). CPAK types I (44.3%), IV (28.6%), and II (10%) were the most common. Regarding AJLO, 70.2% of ankles exhibited varus orientation (mean TPHA was -5.21° ± 6.45°). The most frequent combined subtypes were CPAK type I-A (33.7%), IV-A (21.5%), and I-N (6.9%). A significant positive correlation was found between the TPHA and aHKA (

conclusionIn this North African cohort, varus knee alignment with apex distal JLO and varus AJLO predominated. CPAK types I, IV, and II were the most common types, while subtypes I-A, IV-A, and I-N were commonly occurring after incorporating AJLO types; furthermore, the AJLO was significantly correlated to aHKA.

Indexed as

Ankle joint alignmentCoronal alignmentCoronal plane alignment of the knee classificationKnee arthroplastyKnee replacementNorth African population

Identifiers

PMID41608493
PMCPMC12836154

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