ArticleAesthetic surgery journal. Open forum2025
Synergistic Effects of Autologous Plasma and Agarose Fillers in Treating Acne, Atrophic, and Hypertrophic Scars: A Case Series.
Article in Aesthetic surgery journal. Open forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Quantification and characterization of collagen in experimentally induced wounds treated with different types of platelet-rich plasma gel.Cell and tissue banking · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Scars are a common outcome of wound healing, affecting millions worldwide. These marks can result from various causes. However, current treatments, such as dermal fillers and laser therapy, often have limitations, including transient effects that do not stimulate the body's natural regenerative processes, high costs, and potential adverse reactions. Objectives: The objective of this study is to explore the potential therapeutic synergistic effect of a novel combination therapy using agarose and autologous platelet-rich plasma (PRP) to improve the appearance and characteristics of acne, atrophic, and hypertrophic scars. Methods: This retrospective case series included 8 patients with acne, atrophic, and hypertrophic scars. All participants received a 50/50% mixture of agarose 1% and autologous PRP injected into the affected areas. Acne scars were evaluated using the Goodman and Baron Qualitative Acne Scar Grading System and the Investigator Global Acne Scarring (IGAS) scale. Atrophic and hypertrophic scars were assessed using the Modified Scar Assessment Scale (MSAS) and Investigator Global Aesthetic Improvement Scale (IGAIS). Patient satisfaction for all scar types was measured using the Patient Satisfaction Scale (PSS) at the final follow-up. Results: Combined agarose-PRP therapy demonstrated clinical improvement in all treated scars. Acne scar patients ( Conclusions: Agarose-PRP filler shows promise for scar treatment. Physicians should be aware that these findings may represent an effective treatment option for patients. These results may be helpful in guiding treatment decisions for scar management. Level of Evidence 4 Therapeutic:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.