Evidence map›Paper›PMID 41608443›Full record

ArticleFrontiers in medicine2025

Is there a benefit to adding dexamethasone to levobupivacaine in ultrasound-guided adductor canal block following anterior cruciate ligament reconstruction?

Svetlana Sreckovic, Petar Vukman, Radmila Klacar, Ana Odalovic, Vesna Jovanovic, Miljan Bilanovic, Darko Milovanovic

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Svetlana SreckovicCentre of Anesthesia and Resuscitation, University Clinical Center of Serbia, Belgrade, Serbia.
Petar VukmanClinic for Orthopedics Surgery and Traumatology, University Clinical Center of Serbia, Belgrade, Serbia.
Radmila KlacarCentre of Anesthesia and Resuscitation, University Clinical Center of Serbia, Belgrade, Serbia.
Ana OdalovicCentre of Anesthesia and Resuscitation, University Clinical Center of Serbia, Belgrade, Serbia.
Vesna JovanovicCentre of Anesthesia and Resuscitation, University Clinical Center of Serbia, Belgrade, Serbia.
Miljan BilanovicDepartment of Orthopedic Surgery, University Clinical Hospital Bezanijska Kosa, Belgrade, Serbia.
Darko MilovanovicClinic for Orthopedics Surgery and Traumatology, University Clinical Center of Serbia, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Reconstruction of the anterior cruciate ligament (ACL) often causes severe postoperative pain. This study aimed to assess how dexamethasone affects the analgesic effectiveness of the adductor canal block (ACB), opioid use, and rebound pain after ACL reconstruction with a bone-patellar tendon-bone (BPTB) graft. Methods: This non-randomized prospective study analyzed a total of 160 patients, who were divided into two groups: the Dexamethasone + ACB group and the ACB group. Results: Within the first 24 h after surgery, there was no difference between the groups in the percentage of patients experiencing pain (73.75% vs. 85%; Conclusion: The addition of dexamethasone to the local anesthetic during ACB after ACL reconstruction is not supported due to the lack of benefits related to postoperative pain levels and the associated increase in glucose levels.

Indexed as

adductor blockanterior cruciate ligament reconstructiondexamethasonemultimodal analgesiapostoperative pain

Identifiers

PMID41608443
PMCPMC12834822

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.