Clinical experience with fluoroquinolones for treatment of severe

Binbin Feng, Yueliang Chen, Zhenwei Yu, Shuping Song, Jincheng Ruan, Feng Guo

Abstract read

In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Antimicrobial Management of SevereInfection and drug resistance · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Binbin FengDepartment of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Yueliang ChenDepartment of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Zhenwei YuDepartment of Pharmacy, Zhejiang University School of Medicine, Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, China.

Shuping SongDepartment of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Jincheng RuanDepartment of Anus and Intestine Surgery, The Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.

Feng GuoDepartment of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In this study, we sought to investigate the clinical manifestations, laboratory findings and radiographic features of severe Methods: We retrospectively reviewed the clinical data of 14 patients diagnosed with severe Results: Most patients presented high fever (≥39 °C), shortness of breath and cough, as well as extrapulmonary symptoms such as fatigue, dizziness, muscle pain and headache. There were also significant increases in white blood cells, C-reactive protein (CRP), procalcitonin (PCT), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and D-dimer, while lymphocytes decreased significantly. Primary chest imaging features included consolidation, exudation and pleural effusion. All 14 patients received fluoroquinolones-based treatment and recovered. Conclusion: The clinical manifestations of severe

Indexed as

Chlamydia psittaci pneumoniaclinical characteristicsfluoroquinolonessevere pneumoniatreatment

Identifiers

PMID41608440

DOI10.3389/fmed.2025.1682699

PMCPMC12836392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.