ArticleFrontiers in medicine2025
Risk factors associated with knee osteoarthritis severity and their correlation with Kellgren-Lawrence grade.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Laboratory-selected, probioticFrontiers in nutrition · 2026Trial
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To identify the risk factors associated with knee osteoarthritis (KOA) radiographic severity in a defined cohort of patients with KOA and to examine their associations with Kellgren-Lawrence (K-L) grade. Methods: In this retrospective study, 258 patients with confirmed KOA (100 males and 158 females) diagnosed between July and November 2024 at Shenzhen People's Hospital were enrolled. Demographic and clinical data-including age, sex, body-mass index (BMI), K-L grade, C-reactive protein (CRP) level, and pain intensity assessed by the visual analogue scale (VAS)-were extracted. Sex-related differences in age, K-L grade, BMI, CRP, and VAS were analyzed using the Mann-Whitney Results: (1) Significant gender differences were observed in height, weight, and K-L grade distribution among KOA patients (all Conclusion: In this cross-sectional study, CRP showed a strong association with KOA radiographic severity after adjusting for age, BMI, and pain scores. A numerically stronger association was observed in female patients, though this difference requires further confirmation. These findings highlight the potential role of systemic inflammation in KOA and support the further investigation of CRP as a supplementary clinical assessment tool.
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