ArticleFrontiers in medicine2025
Efficacy evaluation and predictive value of IL-20 and Apelin-13 after cataract surgery by phacoemulsification combined with IOL implantation.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Phacoemulsification combined with intraocular lens (IOL) implantation is the standard treatment for cataract. A proportion of patients still experience suboptimal visual outcomes or postoperative complications. This study aimed to investigate the roles of Interleukin-20 (IL-20) and Apelin-13 as biomarkers for assessing visual outcomes and predicting postoperative prognosis following phacoemulsification with IOL implantation. Methods: In this retrospective study, 193 cataract patients who underwent phacoemulsification combined with IOL implantation between January 2023 and December 2024 were included. Based on the best-corrected visual acuity (BCVA) and complication status at 3 months postoperatively, patients were categorized into good ( Results: There were significant differences in diabetes history, CRP, and IL-6 levels ( Conclusion: IL-20 and Apelin-13 are significantly associated with the efficacy of cataract surgery. Apelin-13 serves as a protective factor for favorable outcomes, whereas IL-20 is a risk factor. Their ratio shows strong predictive value for adverse prognosis. These biomarkers offer potential for preoperative risk assessment and personalized treatment strategies, with significant clinical implications for improving postoperative outcomes.
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