Evidence map›Paper›PMID 41608361›Full record

ArticleCJC pediatric and congenital heart disease2025

Effect of a Systemic Right Ventricle With a Biventricular Circulation on Cardiorespiratory Fitness.

Charles Desrosiers-Gagnon, Naïma-Ayane Mahdi, Michel White, François-Pierre Mongeon, Blandine Mondésert, Annie Dore, Paul Khairy, Daniel Gagnon, Marie-A Chaix

Abstract read
In one paragraph

Article in CJC pediatric and congenital heart disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Systemic Right Ventricle: Is Equal Fitness Truly Equal?CJC pediatric and congenital heart disease · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charles Desrosiers-GagnonResearch Center, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Québec, Canada.
Naïma-Ayane MahdiResearch Center, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Québec, Canada.
Michel WhiteResearch Center, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Québec, Canada.
François-Pierre MongeonResearch Center, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Québec, Canada.
Blandine MondésertResearch Center, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Québec, Canada.
Annie DoreDepartment of Medicine, Adult Congenital Heart Center, Montreal Heart Institute, Université de Montréal, Montreal, Québec, Canada.
Paul KhairyResearch Center, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Québec, Canada.
Daniel GagnonResearch Center, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Québec, Canada.
Marie-A ChaixResearch Center, Montreal Heart Institute, Department of Medicine, Université de Montréal, Montreal, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Adults with transposition of the great arteries and a systemic right ventricle (sRV) generally have lower cardiorespiratory fitness (CRF) than healthy adults with a systemic left ventricle (sLV). However, studies to date have not accounted for systolic function of the systemic ventricle. The objective was to assess and compare CRF in adults with an sRV vs sLV matched for clinical characteristics and systemic ventricular function. Methods: A retrospective cross-sectional analysis was conducted on 24 adults with an sRV and 24 adults with an sLV matched for sex (20 males), age, body mass index, ejection fraction of the systemic ventricle (dysfunction in 23 pairs), New York Heart Association functional class (class II-III in 18 pairs), and doses of diuretics. Peak oxygen consumption ( Results: The population is characterized by high previous heart failure-related hospitalizations (22% in sRV and 58% in sLV) and diagnoses of pulmonary hypertension (61% in sRV and 60% in sLV). Conclusion: No differences in CRF were observed between adults with an sRV and an sLV when matched for clinical characteristics and systemic ventricular function.

Identifiers

PMID41608361
PMCPMC12835908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.