Evidence map›Paper›PMID 41608339›Full record

ArticleWorld journal of clinical oncology2026

Obesity and colorectal cancer risk: A systematic review and meta-analysis.

Lachlan James Chun-Lok Leung, Rohan Sharad Sharma, Brandon Cheng, Hm Kasuni Akalanka, Vinod Gopalan

Abstract read
In one paragraph

Article in World journal of clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lachlan James Chun-Lok LeungSchool of Medicine and Dentistry, Griffith University, Gold Coast 4215, Queensland, Australia. leunglachlan@gmail.com.
Rohan Sharad SharmaSchool of Medicine and Dentistry, Griffith University, Gold Coast 4215, Queensland, Australia.
Brandon ChengSchool of Medicine and Dentistry, Griffith University, Gold Coast 4215, Queensland, Australia.
Hm Kasuni AkalankaRural Health Research Institute, Charles Sturt University, Orange 2800, New South Wales, Australia.
Vinod GopalanSchool of Medicine and Dentistry, Griffith University, Gold Coast 4215, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn observed correlation between increased colorectal cancer (CRC) incidence in patients with obesity [body mass index (BMI) ≥ 30 kg/m

aimTo determine if an updated correlation exists between obesity and the risk of CRC development.

methodsWe evaluated recent data, synthesising pooled estimate effects to determine if an updated correlation exists between obesity and CRC. Observational studies were identified from a range of databases (PubMed, EMBASE, Scopus and the Cochrane database). From the studies identified, sex-stratified meta-analyses were conducted. Additionally, studies included in this review that were unfit for meta-analysis underwent qualitative analysis.

resultsIn a pooled sample size of 83506 male participants obtained from six observational studies, a significant positive correlation between obesity and CRC incidence was identified with a hazard ratio (HR) of 1.71 [95% confidence interval (CI): 1.44-2.02]. A pooled sample size of 152043 female participants from six observational studies also revealed a positive correlation with an HR effect of 1.26 (95%CI: 1.03-1.53). Qualitative analysis of studies not included in the meta-analysis consistently supported this relationship for both sexes.

conclusionObesity, diagnosed by a BMI ≥ 30 kg/m

Indexed as

Body mass indexColorectal cancerMeta-analysisObesitySystematic review

Identifiers

PMID41608339
PMCPMC12835987

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.