Evidence map›Paper›PMID 41608332›Full record

Observational studyCardiovascular therapeutics2026

Elevated Resting Heart Rate in Hospitalized Patients With Atrial Fibrillation Is Associated With Increased Cardiovascular Risk.

Kangning Han, Xia Li, Biao Fu, Mengmeng Li, Tong Liu, Ying Peng, Jing Liu, Na Yang, Yongchen Hao, Chenxi Jiang and 5 more

Abstract readObservational Study
In one paragraph

Observational study in Cardiovascular therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kangning HanDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0000-0001-6603-1895
Xia LiDepartment of Mathematical and Physical Sciences, La Trobe University, Melbourne, Australia, latrobe.edu.au.ORCID https://orcid.org/0000-0003-1890-5548
Biao FuDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0000-0002-8938-4797
Mengmeng LiDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.
Tong LiuDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0000-0001-5372-7236
Ying PengDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0009-0002-5017-6656
Jing LiuDepartment of Epidemiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.
Na YangDepartment of Epidemiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0000-0002-3651-6477
Yongchen HaoDepartment of Epidemiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0000-0002-6519-6185
Chenxi JiangDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.
Ribo TangDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.
Jianzeng DongDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0000-0001-7299-7805
Dong ZhaoDepartment of Epidemiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.
Deyong LongDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0000-0003-4604-5346
Changsheng MaDepartment of Cardiology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China, anzhen.org.ORCID https://orcid.org/0000-0002-5387-5957

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Effective rate control is important in the management of atrial fibrillation (AF). However, the relationship between resting heart rate (RHR) and adverse outcomes in hospitalized patients remains uncertain. Objective: This study was to evaluate the association between RHR and in-hospital outcomes. Methods: Data from the Improving Care for Cardiovascular Disease in China-AF project from 2014 to 2019 were retrospectively analyzed. The primary outcome was the composite of in-hospital all-cause mortality and in-hospital acute heart failure (AHF). Secondary outcomes included stroke/transient ischemic attack (TIA) and bleeding during hospitalization. Logistic regression analyses were used to assess the association between RHR and outcomes. Results: Our study included 12,775 patients hospitalized for AF in 236 hospitals. Logistic regression analyses using different models showed a significant association between RHR exceeding 80 bpm and an increased risk of the primary outcome (adjusted OR: 1.79 [95% CI: 1.44-2.22]). A positive association between RHR and the primary outcome was identified with RHR ≥ 80 bpm. Marginal effect analyses showed that patients with advanced AF types were at higher risk across the range of RHR. Conversely, catheter ablation, but not antiarrhythmic drug use, was associated with a decreased risk. Conclusion: A significant association was identified between RHR and adverse outcomes in patients hospitalized for AF, where RHR exceeding 80 bpm was associated with an increased risk.

Indexed as

Atrial FibrillationHeart FailureHeart RateHospitalizationAgedAnti-Arrhythmia AgentsCatheter AblationChinaFemaleHemorrhageHospital MortalityHumansIschemic Attack, TransientMaleMiddle AgedRetrospective StudiesAnti-Arrhythmia Agentsall-cause mortalityatrial fibrillationheart failureheart rate controlresting heart rate

Identifiers

PMID41608332
PMCPMC12835623

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.