Association between maternal anxiety/depression in pregnancy and the development of offspring eczema/AD: a meta-analysis based on cohort studies.

Mengjiao Yu, Qiufeng Zhang, Junyi Chen, Jingyu Yang, Zhechuan Bai, Junjie Wang

Abstract read

In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mengjiao YuEmergency Medical Center, Ningbo Hospital of Integrated Traditional Chinese and Western Medicine, Ningbo, Zhejiang, China.

Qiufeng ZhangThe Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Junyi ChenThe Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Jingyu YangThe School of Nurse, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Zhechuan BaiThe Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Junjie WangThe Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This meta-analysis investigates the association between maternal anxiety/depression during pregnancy and the development of eczema/atopic dermatitis (AD) in offspring. Methods: A literature search was conducted across four electronic databases (PubMed, Web of Science, Embase, and the Cochrane Library) for studies published from database inception until July 2025. In this study, maternal depression and anxiety were defined as conditions physician-diagnosed or assessed with standardized scales during pregnancy. The primary outcome was the incidence of eczema/AD in the offspring. Result: A total of 12 cohort studies were included in this meta-analysis. Pooled results indicated that maternal depression [odds ratio (OR) = 1.06, 95% confidence interval (95% CI) = 1.01-1.11, Conclusion: This study suggests that maternal depression/anxiety during pregnancy is potentially associated with the development of eczema/AD in offspring.

Indexed as

anxietyatopic dermatitisdepressioneczemamaternaloffspring

Identifiers

PMID41608327

DOI10.3389/fped.2025.1734662

PMCPMC12835386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.