ArticlePulmonary circulation2026
Percutaneous Reperfusion Therapies vs. Anticoagulation in Patients With Acute Intermediate-High-Risk Pulmonary Embolism: The PRETHA Randomized Clinical Trial.
Article in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The optimal treatment strategy for patients with acute intermediate-high-risk pulmonary embolism (PE) remains uncertain. This randomized clinical trial (PRETHA) aimed to evaluate the efficacy and safety of percutaneous reperfusion therapies-trans-catheter thrombectomy and trans-catheter thrombolysis-compared with standard anticoagulation therapy. In this single-center, prospective trial conducted between April 2020 and April 2022, 39 patients with acute intermediate-high-risk PE were randomly assigned (1:1:1) to receive trans-catheter thrombectomy, trans-catheter thrombolysis, or conservative medical therapy with anticoagulation. Echocardiographic, hemodynamic, and biomarker parameters were assessed at baseline, 48 h, and at 1-, 6-, and 12-month follow-up. At 48 h, both interventional groups demonstrated significant improvement in right ventricular (RV) function and pulmonary pressures. The RV/LV ratio decreased by 0.3 (95% CI: 0.13-0.69;
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