ReviewJuntendo medical journal2025
Diagnosis and Management of Heat-related Illness: Clinical and Molecular Perspectives.
Review in Juntendo medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- [Heat-related illnesses in emergency and intensive care medicine : Consensus paper of the German Society for Internal Intensive Care and Emergency Medicine (DGIIN) and the German Association for Emergency Medicine (DGINA)].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Review
- Review
- Acute Heat Exposure-Related Illness: A Unified Emergency Medicine Framework for Hot Baths, Hot Springs, and Saunas-A Narrative Review.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat-related illness (HRI) represents a growing public health challenge in the context of global warming. Ranging from mild symptoms such as heat cramps to life-threatening heatstroke, HRI requires prompt recognition and appropriate management to reduce morbidity and mortality. The diagnosis of HRI is primarily based on clinical symptoms but is supported by laboratory evaluation, especially in severe cases. Heatstroke, the most critical form, is defined by core body temperature ≥ 40°C and central nervous system dysfunction. In addition to conventional laboratory markers, recent advances in molecular biology have identified several biomarkers, such as heat shock proteins, HMGB1 (High Mobility Group Box 1), and mitochondrial DNA, which may improve early and accurate detection and prognostication. This review summarizes the diagnostic approach to HRI, highlighting key clinical findings, laboratory assessments, and emerging molecular markers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.