Evidence map›Paper›PMID 41608000›Full record

ArticleCureus2025

Correlation Between Myopia Degree and Postoperative Dry Eye Disease in Keratorefractive Lenticule Extraction Surgery.

Chia-Yi Lee, Shun-Fa Yang, Yu-Ling Chang, Jing-Yang Huang, Feng-Ming Yeh, Chao-Kai Chang

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chia-Yi LeeInstitute of Medicine, Chung Shan Medical University, Taichung, TWN.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung, TWN.
Yu-Ling ChangDepartment of Pediatric Medicine, Cathay General Hospital, Taipei, TWN.
Jing-Yang HuangDepartment of Medical Research, Chung Shan Medical University Hospital, Taichung, TWN.
Feng-Ming YehDepartment of Optometry, Yuanpei University of Medical Technology, Hsinchu, TWN.
Chao-Kai ChangDepartment of Ophthalmology, Nobel Eye Institute, Taipei, TWN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate the relationship between myopia degree and the rate of postoperative dry eye disease (DED) in participants who received keratorefractive lenticule extraction (KLEx) surgery.

methodsA retrospective cohort study was conducted, and participants who received KLEx surgery were included. After selection, a total of 95 and 76 eyes were classified into the low myopia (LM) and high myopia (HM) groups, respectively. The main outcomes are the postoperative tear break-up time (TBUT), Schirmer test, ocular surface staining, and DED-related symptoms. The independent t-test and generalized linear model were used for the statistical analysis of the present study.

resultsThe postoperative uncorrected distance visual acuity (UDVA) and spherical equivalent (SE) were significantly better in the LM group (all p<0.001). Regarding the postoperative DED parameters, the TBUT and Schirmer test values were significantly higher in the LM group compared to those in the HM group during the whole follow-up period (all p<0.05). The rate of superficial keratitis and multiple DED symptom were significantly higher in the HM group than the LM group one month postoperatively (both p<0.05). Advanced age correlated with poor DED sign, and female sex correlated with poor DED symptom in the LM group (both p<0.05). On the other hand, both advanced age and female sex were associated with poor DED signs and symptoms in the HM group (all p<0.05).

conclusionHM may have a certain correlation with higher DED incidence and severity for participants who received KLEx surgery.

Indexed as

dry eye diseasekeratorefractive lenticule extractionmyopiasuperficial keratitisvisumax 800

Identifiers

PMID41608000
PMCPMC12836437

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