ArticleCureus2025
Spontaneous Pneumomediastinum Presenting as Dysphonia.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spontaneous pneumomediastinum is a rare condition describing air within the mediastinum from a non-traumatic etiology from an intrathoracic or extrathoracic source. It typically affects young men through a mechanism known as the Macklin effect, in which alveolar air travels along bronchovascular sheaths into the mediastinum. There are known predisposing conditions as well as activities that can precipitate spontaneous pneumomediastinum, which is generally self-limited, but in rare circumstances, can lead to serious complications such as tension pneumomediastinum, mediastinitis, and tension pneumothorax. The classic triad of symptoms for this condition includes chest pain, subcutaneous emphysema, and dyspnea. We present a case of spontaneous pneumomediastinum in a 19-year-old male patient with the chief complaint of dysphonia after repeated heavy lifting three days prior to presentation. Spontaneous mediastinum after heavy lifting has been reported previously; however, our case is unique in that the patient presented with dysphonia without chest pain or dyspnea. This condition is important to keep in mind as spontaneous pneumomediastinum is typically self-limiting and can be managed conservatively, reducing unnecessary resource utilization. A chest radiograph is the diagnostic test of choice, and further diagnostic studies may not be necessary. In our case, aerodigestive injury was ruled out with a swallow study because there was a history of occasional vomiting and an unknown source of pneumomediastinum. Although spontaneous pneumomediastinum more commonly presents with chest pain and dyspnea, it is an overall rare condition and should be considered in cases of dysphonia as well, as in this case. Prompt diagnosis of spontaneous pneumomediastinum is important to both monitor for complications and avoid overtreatment.
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