Evidence map›Paper›PMID 41607981›Full record

ArticleCureus2025

Spontaneous Pneumomediastinum Presenting as Dysphonia.

Jacob Weaver, Rachel Cox, Eric Karr

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jacob WeaverInternal Medicine, Wright State University, Dayton, USA.
Rachel CoxInternal Medicine, Wright State University, Dayton, USA.
Eric KarrInternal Medicine, Wright State University, Dayton, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous pneumomediastinum is a rare condition describing air within the mediastinum from a non-traumatic etiology from an intrathoracic or extrathoracic source. It typically affects young men through a mechanism known as the Macklin effect, in which alveolar air travels along bronchovascular sheaths into the mediastinum. There are known predisposing conditions as well as activities that can precipitate spontaneous pneumomediastinum, which is generally self-limited, but in rare circumstances, can lead to serious complications such as tension pneumomediastinum, mediastinitis, and tension pneumothorax. The classic triad of symptoms for this condition includes chest pain, subcutaneous emphysema, and dyspnea. We present a case of spontaneous pneumomediastinum in a 19-year-old male patient with the chief complaint of dysphonia after repeated heavy lifting three days prior to presentation. Spontaneous mediastinum after heavy lifting has been reported previously; however, our case is unique in that the patient presented with dysphonia without chest pain or dyspnea. This condition is important to keep in mind as spontaneous pneumomediastinum is typically self-limiting and can be managed conservatively, reducing unnecessary resource utilization. A chest radiograph is the diagnostic test of choice, and further diagnostic studies may not be necessary. In our case, aerodigestive injury was ruled out with a swallow study because there was a history of occasional vomiting and an unknown source of pneumomediastinum. Although spontaneous pneumomediastinum more commonly presents with chest pain and dyspnea, it is an overall rare condition and should be considered in cases of dysphonia as well, as in this case. Prompt diagnosis of spontaneous pneumomediastinum is important to both monitor for complications and avoid overtreatment.

Indexed as

chest paincomputed tomography (ct)dysphonia workupdyspneaesophagramhamman’s syndromemacklin effectpneumomediastinum (pm)spontaneous pneumomediastinum (spm)subcutaneous emphysema

Identifiers

PMID41607981
PMCPMC12839783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.