Evidence map›Paper›PMID 41607900›Full record

SynthesisFrontiers in public health2025

The role, challenges, and solutions of laboratories in disaster medicine: a systematic review.

Kien Trung Tran, Ky Dinh Nguyen, Tho Ngoc Nguyen, Lam The Pham, Linh Mai Nguyen, Phong Han Nguyen, Nam Hoang Tran, Chung Thi Kim Le

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kien Trung TranHanoi Medical University, Hanoi, Vietnam.
Ky Dinh NguyenHanoi Medical University, Hanoi, Vietnam.
Tho Ngoc NguyenHanoi Medical University, Hanoi, Vietnam.
Lam The PhamHanoi Medical University, Hanoi, Vietnam.
Linh Mai NguyenHanoi Medical University, Hanoi, Vietnam.
Phong Han NguyenHanoi Medical University, Hanoi, Vietnam.
Nam Hoang TranTokushima University, Tokushima, Japan.
Chung Thi Kim LeHanoi Medical University, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Laboratory systems play a critical role in disaster response, yet evidence remains fragmented. This systematic review aimed to describe the roles of clinical, public health, and veterinary laboratories, specifically characterizing Point-of-Care Testing (POCT) and Mobile Laboratories (ML) as flexible operational extensions of the central laboratory system across disaster phases; identify and compare laboratory-related challenges by disaster type; and synthesize documented solutions and their effectiveness. Methods: 4,323 studies published between 2000 and 2025 were identified through searches in PubMed, Embase, Scopus, grey literature, and snowballing. Study screening, data extraction, and methodological quality appraisal were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement. Risk of bias was assessed using the critical appraisal checklist for qualitative research developed by the Joanna Briggs Institute (JBI). Results: Fifty-two studies were included. While clinical, public health, and veterinary laboratories form the "National Core Layer," POCT and rapid response mobile laboratory were identified as the "Surge Capacity Layer," functioning as flexible extended arms. Instead of random barriers, laboratory challenges were found to align along three operational axes: (1) Scarcity (infrastructure fragility and workforce shortages), predominantly in low-resource settings; (2) Complexity (data fragmentation and quality assurance variability), driven by technological heterogeneity in high-income settings; and (3) Security (regulatory barriers and cybersecurity risks), characterizing conflict and bio-risk environments. Documented solutions showed mixed effectiveness. Conclusion: Building on these insights, we propose a structured framework to guide scalable strategies that enhance laboratory system resilience for disaster preparedness and response. Systematic review registration: The protocol was prospectively registered in PROSPERO (CRD420251053068) https://www.crd.york.ac.uk/PROSPERO/view/CRD420251053068.

Indexed as

Disaster MedicineLaboratoriesHumansPublic Healthdisaster medicinedisaster planningemergency medical serviceslaboratoriessolutions

Identifiers

PMID41607900
PMCPMC12834775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.