Evidence map›Paper›PMID 41607868›Full record

ArticleJournal of arrhythmia2026

Percutaneous Left Atrial Appendage Occlusion for Atrial Fibrillation in Cardiac Amyloidosis.

Abdul Hakim Almakadma, Ramzi Ibrahim, Hoang Nhat Pham, Eiad Habib, Ahmed K Mahmoud, Kamal Awad, Mayurkumar D Bhakta, Eric H Yang, Hicham Z El Masry, Chadi Ayoub and 1 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdul Hakim AlmakadmaDepartment of Medicine Brookdale University Hospital Brooklyn New York USA.
Ramzi IbrahimDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.
Hoang Nhat PhamDepartment of Cardiovascular Medicine Mayo Clinic Rochester Minnesota USA.
Eiad HabibDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.
Ahmed K MahmoudDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.
Kamal AwadDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.ORCID https://orcid.org/0000-0001-6707-1629
Mayurkumar D BhaktaDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.
Eric H YangDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.
Hicham Z El MasryDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.ORCID https://orcid.org/0000-0002-2470-2862
Chadi AyoubDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.ORCID https://orcid.org/0000-0002-7118-2302
Reza ArsanjaniDepartment of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac amyloidosis (CA) is frequently complicated by atrial fibrillation (AF), yet outcomes after left atrial appendage occlusion (LAAO) in this population remain poorly defined. Methods: We conducted a retrospective TriNetX study of adults with AF undergoing LAAO, comparing patients with and without CA after 1:1 propensity matching. Outcomes were assessed using Kaplan-Meier analyses and Cox regression. Results: Among 532 matched pairs, mortality and major adverse cardiovascular events were similar between groups, whereas major bleeding was higher in CA (HR 1.90). Conclusions: LAAO yields comparable ischemic outcomes in CA, though bleeding risk is increased.

Identifiers

PMID41607868
PMCPMC12835604

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.