Evidence map›Paper›PMID 41607812›Full record

ArticleWorld journal of transplantation2026

Silent cardiac burden: Echocardiographic abnormalities and their predictors in kidney transplant candidates and their impact on graft function.

Nihal Mohammed Sadagah, Muhammad Abdul Mabood Khalil, Hinda Hassan Khideer Mahmood, Ibtisam Ali Alghamdi, Ghada Abdulrahman Buridi, Salem H Al-Qurashi

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Article in World journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nihal Mohammed SadagahCenter of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital Jeddah, Jeddah 23311, Saudi Arabia.
Muhammad Abdul Mabood KhalilCenter of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital Jeddah, Jeddah 23311, Saudi Arabia. doctorkhalil1975@hotmail.com.
Hinda Hassan Khideer MahmoodCenter of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital Jeddah, Jeddah 23311, Saudi Arabia.
Ibtisam Ali AlghamdiDepartment of Medicine, King Fahad Armed Forces Hospital, Jeddah 23311, Makkah al Mukarramah, Saudi Arabia.
Ghada Abdulrahman BuridiDepartment of Medicine, King Fahad Armed Forces Hospital, Jeddah 23311, Makkah al Mukarramah, Saudi Arabia.
Salem H Al-QurashiCenter of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital Jeddah, Jeddah 23311, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn echocardiogram is an essential tool in the evaluation of potential kidney transplant recipients (KTRs). Despite cardiac clearance, potential KTRs still have structural and functional abnormalities. Identifying the prevalence of these abnormalities and understanding their predictors is vital for optimizing pre-transplant risk stratification and improving post-transplant outcomes.

aimTo determine the prevalence of left ventricular hypertrophy (LVH), left ventricular systolic dysfunction (LVSD), diastolic dysfunction (DD), pulmonary hypertension (PH), and their predictors, and to assess their impact on graft function in pre-transplant candidates.

methodsThe study included all successful transplant candidates older than 14 who had a baseline echocardiogram. Binary logistic regression models were constructed to identify factors associated with LVH, LVSD, DD, and PH.

resultsOut of 259 patients, LVH was present in 64% (166), 12% (31) had LVSD, 27.5% (71) had DD, and 66 (25.5%) had PH. Independent predictors of LVH included male gender [odds ratio (OR): 2.51; 95%CI: 1.17-5.41

conclusionSignificant echocardiographic abnormalities persist in a potential transplant candidate despite cardiac clearance, although they don't affect future graft function. Understanding the risk factors associated with these abnormalities may help clinicians address these factors pre- and post-transplant to achieve better outcomes.

Indexed as

Echocardiographic abnormalitiesGraft functionKidney transplantPredictors

Identifiers

PMID41607812
PMCPMC12836241

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