Evidence map›Paper›PMID 41607790›Full record

ArticleFrontiers in immunology2025

CD82-associated exhausted CD8

Jingfeng Zhang, Hengwei Cui, Shaoxian Wu, Hongwei Shi, Haitao Wang, Jingting Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biomedicines · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingfeng Zhang *Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Hengwei Cui *Trauma Center, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Shaoxian WuDepartment of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Hongwei ShiDepartment of Gastrointestinal Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Haitao WangDepartment of Gastrointestinal Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Jingting JiangDepartment of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regulation of T cell exhaustion within the tumor microenvironment plays a pivotal role in shaping the immune response to cancer and determining the efficacy of immunotherapy. However, the molecular factors governing this process in colon cancer remain poorly understood. This study investigates the expression characteristics and functional significance of the transmembrane protein CD82 in the colon cancer immune microenvironment, with emphasis on its regulatory role in CD8

Indexed as

CD8-Positive T-LymphocytesColonic NeoplasmsDrug Resistance, NeoplasmKangai-1 ProteinBiomarkers, TumorHumansImmunotherapyLymphocytes, Tumor-InfiltratingMalePrognosisT-Cell ExhaustionTumor MicroenvironmentBiomarkers, TumorCD82 protein, humanKangai-1 ProteinCD82colon cancerexhausted CD8+ T cellsmulti-color immunohistochemistryprognosis

Identifiers

PMID41607790
PMCPMC12835202

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.