Evidence map›Paper›PMID 41607718›Full record

ArticleCJC pediatric and congenital heart disease2025

Prevalence and Impact of Partial Anomalous Pulmonary Venous Connection in Turner Syndrome.

Estelle Tenisch, Silvia Gigliotti, Jenny Lam, Kanetee Busiah, Peter Kopp, Florence Niel-Bütschi, Nelly Pitteloud, Judith Bouchardy, Nicole Sekarski, Magalie Ladouceur and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CJC pediatric and congenital heart disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Estelle TenischPediatric Radiology Unit, Department of Medical Imaging and Interventional Radiology, Lausanne University Hospital and University of Lausanne, University of Lausanne, Lausanne, Switzerland.
Silvia GigliottiCongenital Heart Disease Unit, Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Jenny LamPaediatric Endocrinology, Diabetology and Obesity Unit, Women-Mothers-Children Department, Lausanne University Hospital and University of Lausanne, University of Lausanne, Lausanne, Switzerland.
Kanetee BusiahPaediatric Endocrinology, Diabetology and Obesity Unit, Women-Mothers-Children Department, Lausanne University Hospital and University of Lausanne, University of Lausanne, Lausanne, Switzerland.
Peter KoppDivision of Endocrinology, Diabetes & Metabolism, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
Florence Niel-BütschiLaboratory Medicine and Pathology Unit, Genetic Labs Department, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nelly PitteloudDivision of Endocrinology, Diabetes & Metabolism, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
Judith BouchardyCongenital Heart Disease Unit, Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Nicole SekarskiPediatric Cardiology Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Magalie LadouceurCongenital Heart Disease Unit, Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Tobias RutzCongenital Heart Disease Unit, Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with Turner syndrome (TS) have a higher mortality than age-matched females, mainly due to cardiovascular disorders. Recently, an increased prevalence of partial anomalous pulmonary venous connection (PAPVC) was described in patients with TS. However, data on the clinical impact of PAPVC, that is, the need for surgical correction, are scarce. This study aimed at evaluating the prevalence and impact of congenital heart disease (CHD) with a focus on PAPVC in a TS population. Methods: Patients with TS of all ages were included. Clinical data and reports of echocardiography, cardiac magnetic resonance (CMR), or computed tomography (CT) were retrospectively evaluated. CMR and CT were reviewed for PAPVC. Results: Seventy-nine patients with TS were included (53 adults, 26 children [mean age 25 years, range 5-67 years]). Sixty-five patients underwent echocardiography, 41 CMR, and 3 CT. Cardiovascular disorders were present in 45% of patients and more frequently in karyotype monosomy X (76%), followed by 45, X mosaicism (39%), X structural rearrangements (18%), and other, unknown (16%) ( Conclusions: The spectrum of cardiovascular disorders in TS appears to be associated with the karyotype. Among CHD lesions, bicuspid aortic valve is the most prevalent, followed by PAPVC, although the latter seems to have a minor impact on outcome. However, PAPVC is systematically missed on echocardiography and classically found in patients with complete monosomy X.

Indexed as

aortic valvecardiac MRI-bicuspidcongenital heart diseasepartial anomalous pulmonary venous connectionTurner syndrome

Identifiers

PMID41607718
PMCPMC12835978

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.