ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2026
Can implementation of a complex outpatient antimicrobial therapy program reduce readmissions for patients with bone and joint infections?
Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Evaluate whether a complex outpatient antimicrobial therapy (COpAT) program led by advanced practice providers (APPs) conducting transition-of-care (TOC) services improves post discharge patient follow-up and reduces hospital readmission. Design: Pre- and postimplementation cohort study comparing outcomes 6 months before and 5 months after COpAT launch. Setting: 706-bed tertiary university teaching hospital. Patients: Adult patients admitted to the hospital with bone and joint infections, seen by our inpatient infectious disease consultation service and discharged with at least fourteen days of antimicrobial therapy, with follow-up at our specialized musculoskeletal infectious diseases clinic. Intervention: The APP led pilot COpAT program was launched on March 1 Results: The pre- and post-intervention groups included 100 and 135 patients, respectively. Mean postdischarge follow-up time decreased from 20.1 to 9.1 days ( Conclusion: A structured, COpAT program with APP and TOC pharmacy involvement optimizes postdischarge follow-up, strengthens antimicrobial outpatient monitoring, and supports timely intervention for patients with complex infections.
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