Evidence map›Paper›PMID 41607652›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Admixture mapping identifies complex trait associations with local ancestry in the

Wilfredo G Gonzalez Rivera, Youwen Liu, Tara Mirmira, Nichole Ma, Jihoon Kim, Matteo D' Antonio, Umber Dube, Kelly A Frazer, Melissa Gymrek

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wilfredo G Gonzalez RiveraBioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, CA, USA.
Youwen LiuDepartment of Biomedical Informatics & Data Science, Yale University, New Heaven, CT, USA.
Tara MirmiraDepartment of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA.
Nichole MaDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Jihoon KimDepartment of Biomedical Informatics & Data Science, Yale University, New Heaven, CT, USA.
Matteo D' AntonioMedicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Umber DubeDepartment of Dermatology, University of California San Diego, La Jolla, CA, USA.
Kelly A FrazerDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.
Melissa GymrekDepartment of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-6086-3903

Funding

Genetic & Social Determinants of Health: Center for Admixture Science and TechnologyRM1HG011558 · NHGRI · YALE UNIVERSITY · PI FRAZER, KELLY A, GYMREK, MELISSA · 2021 to 2025
$11.2M
San Diego Biomedical Informatics Education & Research (SABER)T15LM011271 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2012 to 2026
$9.7M
NHGRI NIH HHS RM1 HG011558NLM NIH HHS T15 LM011271
6 · The paper itself

Abstract

Genetic studies have largely focused on homogeneous populations, limiting our understanding of the genetic architecture of complex traits in admixed individuals. The advent of diverse biobanks like the

Identifiers

PMID41607652
PMCPMC12838303

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.