Evidence map›Paper›PMID 41607490›Full record

ArticleJournal of human immunity2025

Disseminated gonococcal infection secondary to a rare homozygous mutation resulting in complement factor I deficiency.

Marianna Almpani, Geoffrey Welch, Emma Vanderleeden, Jutamas Shaughnessy, Qadija Qadri, Doyle V Ward, Juan M Perez-Velazquez, Sanjay Ram, Jennifer P Wang

Abstract read
In one paragraph

Article in Journal of human immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marianna AlmpaniDivision of Infectious Diseases and Immunology, Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0003-1703-7531
Geoffrey WelchDivision of Infectious Diseases and Immunology, Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0002-5968-3913
Emma VanderleedenDepartment of Medicine, Diabetes Center of Excellence, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0009-0005-5339-1863
Jutamas ShaughnessyDivision of Infectious Diseases and Immunology, Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0003-0832-9954
Qadija QadriDivision of Infectious Diseases and Immunology, Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0009-0005-4156-2098
Doyle V WardDepartment of Microbiology, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0002-4952-824X
Juan M Perez-VelazquezDivision of Infectious Diseases and Immunology, Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0009-0005-0416-6037
Sanjay RamDivision of Infectious Diseases and Immunology, Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0003-0058-9532
Jennifer P WangDepartment of Medicine, Diabetes Center of Excellence, UMass Chan Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0002-2556-9100

Funding

Sialic acid analogs against multidrug-resistant gonorrheaR01AI160247 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MOSS, JOHN A, RAM, SANJAY · 2021 to 2025
$5.1M
NIAID NIH HHS R01 AI160247
6 · The paper itself

Abstract

A 34-year-old male presented with recurrent fever, arthralgia, and rash. He had two prior hospitalizations for suspected vasculitis and meningococcal meningitis at age 13 years. Positive blood cultures for

Identifiers

PMID41607490
PMCPMC12829745

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.