ReviewOrthopaedic journal of sports medicine2026
Chemoprophylaxis for Heterotopic Ossification After Hip Arthroscopy: A Systematic Review and Meta-analysis.
Review in Orthopaedic journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Heterotopic ossification (HO) is a common complication after hip arthroscopy that has historically been prophylactically treated with postoperative radiation. Newer prophylactic treatments use nonsteroidal anti-inflammatory drugs (NSAIDs) in place of radiation. Purpose: To examine the incidence of HO after hip arthroscopy with and without the use of chemoprophylactic agents. Study Design: Systematic review; Level of evidence, 4. Methods: PubMed and Scopus electronic databases were queried for all studies published between January 2000 and July 2025 that evaluated HO after hip arthroscopy. Information on study design, the use of exclusive NSAID chemical prophylaxis and regimen, presence of HO, and length of follow-up were collected from all studies. The Brooker classification was used for determining severity of HO. Matched-cohort studies were combined for meta-analysis and analyzed using the DerSimonian and Laird method of random-effects meta-analysis. Results: A total of 44 studies including a total of 32,603 patients were included. The incidence of HO in patients who received chemoprophylaxis after hip arthroscopy was 15.3 per 1000 patients per year compared with 80.1 per 1000 patients per year in those who did not receive chemoprophylaxis ( Conclusion: Postoperative NSAIDs were effective in reducing the incidence and severity of HO after hip arthroscopy. Meta-analysis of matched-cohort studies estimated a 10-fold decrease in the incidence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.