ArticleFrontiers in endocrinology2025
Neutrophil-to-lymphocyte ratio in females as a predictor of embryo acquisition outcomes after IVF/ICSI treatment: a retrospective study.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: We aimed to analyze the correlation between the neutrophil-to-lymphocyte ratio (NLR), and the treatment outcomes for infertile women after Methods: This retrospective study enrolled women with infertility at Huzhou Maternal and Child Health Care Hospital who underwent Results: Multimodal adjusted logistic regression analysis revealed a significant association between the second quartile of NLR and negative outcomes of IVF treatment, with an OR value and 95% confidence interval of 0.28 (0.10-0.67). The area under the ROC curve was 0.850 <. We observed an interaction between NLR quartiles and infertility types, particularly positive correlations between primary infertility, female-specific infertility factors, and no history of miscarriage with IVF outcomes at the second quartile. When the second quartile was adjusted as a reference value, the three remaining quartiles exhibited statistically significant differences compared to the second quartile ( Conclusion: We recommended dynamically monitoring NLR during the cycle of ovulation induction and advocating individualized inflammatory management based on the cause of infertility to ensure the effectiveness of IVF treatment and prevent resource wastage.
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