ArticleFrontiers in endocrinology2025
Sarcopenic obesity and history of falls in older Italian adults: associations according to different diagnostic combinations.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Sarcopenic obesity (SO) is characterized by the coexistence of sarcopenia and excess adipose tissue, increasing the risk of falls and related adverse outcomes in older adults. However, diagnostic criteria for SO remain inconsistent, warranting further investigation. This study aimed to examine the association between SO, defined according to the criteria proposed by the 2022 European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity (EASO), and the history of falls among hospitalized older Italian adults. Methods: This cross-sectional study included 90 older Italian adults (≥ 60 years) with severe obesity (body mass index ≥ 35 kg/m Results: Significant associations between SO and falls were found only when muscle function was assessed using HGS, regardless of the method used to estimate FM% and muscle mass. In adjusted analyses, participants classified as having SO according to combinations HGS + FM% BIA + SMM/W and HGS + FM% DXA + AMM/W had approximately almost fourfold (OR=3.61; 95% CI: 1.28-10.19) and sixfold (OR=6.03; 95% CI: 1.80-20.23) higher odds of reporting falls in the previous year, respectively, when compared to those without SO considering the same diagnostic tests. Conclusion: SO defined by low HGS combined with high FM% and low muscle mass adjusted for body weight-whether measured using DXA or BIA-was associated with greater odds of falls in older Italian adults. These findings support the use of muscle strength-based definitions of SO when evaluating fall risk in this population.
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