Evidence map›Paper›PMID 41607453›Full record

ArticleWorld journal of psychiatry2026

Tail clamping induces anxiety-like behaviors and visceral hypersensitivity in rat models of non-erosive reflux disease.

Mi Lv, Xin Liu, Kai-Yue Huang, Yu-Xi Wang, Zheng Wang, Li-Li Han, Hui Che, Lin Lv, Feng-Yun Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mi LvInstitute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Xin LiuGraduate School, Beijing University of Chinese Medicine, Beijing 100029, China.
Kai-Yue HuangInstitute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Yu-Xi WangGraduate School, Beijing University of Chinese Medicine, Beijing 100029, China.
Zheng WangDepartment of Gastroenterology, Peking University Health Science Center, Beijing 100191, China.
Li-Li HanInstitute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Hui CheInstitute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Lin LvInstitute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Feng-Yun WangInstitute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China. 18810631761@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-erosive reflux disease (NERD), the main gastroesophageal reflux subtype, features reflux symptoms without mucosal damage. Anxiety links to visceral hypersensitivity in NERD, yet mechanisms and animal models are unclear.

aimTo establish a translational NERD rat model with anxiety comorbidity

methodsSprague-Dawley (SD) and Wistar rats were grouped into sham, model, and modified groups (

resultsTail clamping induced anxiety, worsening visceral hypersensitivity (lower abdominal withdrawal reflex thresholds,

conclusionTail clamping induces anxiety in NERD models, worsening visceral hypersensitivity

Indexed as

Animal modelAnxiety and depressionCorticotropin hormonesNon-erosive reflux diseaseTail-clamping

Identifiers

PMID41607453
PMCPMC12836238

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.