ArticleWorld journal of psychiatry2026
Analysis the incidence and related risk factors of depression in patients with esophageal cancer combined with bone metastasis.
Article in World journal of psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundEsophageal cancer is highly malignant and frequently metastasizes to bones. Concomitant depression worsens prognosis; however, its incidence and determinants in this specific population remain poorly defined.
aimTo determine the incidence of depression and its independent risk factors in patients with esophageal cancer and bone metastasis.
methodsA total of 100 consecutive eligible patients admitted between March 2022 and March 2025 were recruited. Depression was assessed with the Beck Depression Inventory-II; scores > 4 defined the depression group (
resultsDepression prevalence was 42.0% (42/100). Univariate analysis demonstrated significant differences in monthly per-capita household income, education level, social support, sleep disorders, and serum high-sensitivity C-reactive protein (all
conclusionDepression is common among patients with esophageal cancer and bone metastasis. Low socioeconomic status, limited education, insufficient social support, sleep disturbances, and systemic inflammation were independent predictors. Interventions that address these modifiable factors may reduce depression risk in this population.
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