ReviewNanomedicine (London, England)2026
Antimicrobial nanocoatings and films for contact lenses: progress and promise.
Review in Nanomedicine (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMicrobial keratitis is a serious complication of contact lens wear, occurring in 2-24 cases per 10,000 wearers annually. Increasing lens use, especially for myopia control in children, highlights the need for safer designs. Antimicrobial coatings and films offer a promising strategy to reduce infection risk. Recent approaches include metallic and polymeric nanocoatings, antimicrobial peptides (AMPs), peptidomimetics, and hybrid systems that prevent microbial adhesion and biofilm formation while maintaining lens biocompatibility. AREAS COVERED: This review examines advances in antimicrobial nanocoatings for contact lenses, focusing on metallic nanoparticles (silver, zinc oxide, titanium dioxide), organo-selenium coatings, polymeric layers, AMPs such as melimine and Mel4, and emerging peptidomimetics. Literature from PubMed, Scopus, and Web of Science (2008-2025) was analyzed. Key topics include coating techniques (surface grafting, dip-coating, plasma treatment), antimicrobial mechanisms, and outcomes from preclinical and clinical trials. Limitations such as nanoparticle toxicity, peptide degradation, and regulatory hurdles are discussed. EXPERT OPINION/COMMENTARY: Antimicrobial nanocoatings show strong potential, achieving >3-log
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.