ArticleJournal of oral & facial pain and headache2026
Pain modulation profiles in temporomandibular disorders with migraine and fibromyalgia.
Article in Journal of oral & facial pain and headache, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTemporomandibular disorders (TMD) frequently occur with other pain conditions, and existing research has yielded mixed results regarding the presence or absence of endogenous pain modulation (EPM). This study aimed to investigate EPM in TMD patients with comorbid migraine and fibromyalgia (FM) in the non-trigeminal innervated area.
methodsConditioned pain modulation (CPM) and temporal summation (TS) were assessed in healthy controls (n = 30), TMD without comorbidity (n = 30), migraine (n = 30), TMD with migraine (n = 30), and TMD with migraine + FM (n = 19). Based on the TS and CPM responses, participants were categorized into pain modulation profiles (PMP, I-IV).
resultsIn serial stimulation, patients with migraine, TMD + migraine, and TMDs + migraine + FM showed significantly reduced pain inhibition compared with controls (
conclusionsTMD patients without comorbid pain exhibited intact EPM in non-painful areas. However, when these individuals experience comorbid pain conditions, their ability to modulate pain may be compromised due to the pain amplification and central sensitization associated with multiple comorbid pain conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.