Evidence map›Paper›PMID 41607321›Full record

ReviewJournal of oral & facial pain and headache2026

Association between temporomandibular disorders and somatization: a narrative review.

Qing Xue, Hongyu Ming, Yi Huang, Xin Xiong

Abstract readReview
In one paragraph

Review in Journal of oral & facial pain and headache, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qing XueDepartment of Stomatology, The Second Affiliated Hospital of Shandong First Medical University, 271000 Tai'an, Shandong, China.
Hongyu MingState Key Laboratory of Oral Diseases, National Centre for Stomatology, and National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 610041 Chengdu, Sichuan, China.ORCID 0009-0005-9946-7114
Yi HuangCentre for Research and Development, Pan-European University, 821 02 Bratislava, Slovakia.
Xin XiongState Key Laboratory of Oral Diseases, National Centre for Stomatology, and National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 610041 Chengdu, Sichuan, China.ORCID 0000-0003-2175-0970

Funding

Clinical Research Project of West China Hospital of Stomatology, Sichuan University LCYJ-2023- YY-2National Natural Science Foundation of China 82301129Natural Science Foundation of Sichuan Province of China-Youth Fund Project 2025ZNSFSC1586
6 · The paper itself

Abstract

Temporomandibular disorders (TMD) are common orofacial pain conditions with multifactorial etiologies. Somatization refers to the manifestation of psychological distress as physical symptoms in the absence of clear medical causes. A growing body of clinical research has recently shown a strong association between TMD and somatization. A substantial proportion of TMD patients exhibit moderate to high levels of somatic symptoms, leading to greater pain intensity, longer disease duration, and heightened psychological distress. The TMD-somatization relationship has been underpinned by complex pathophysiological interactions and the underlying mechanisms involved, including central sensitization (CS), potential biomarkers, nociplastic pain, neurobiological changes, and so on. Clinically, recognizing somatization in TMD patients is essential, as it can adversely affect treatment outcomes and necessitate a biopsychosocial management approach. In this narrative review, we summarize the clinical evidence of the TMD-somatization association, discuss the underlying mechanisms, explore management implications, and identify directions for future research.

Indexed as

Somatoform DisordersTemporomandibular Joint DisordersFacial PainHumansNociplastic PainBiopsychosocialOrofacial painSomatizationTemporomandibular disorders

Identifiers

PMID41607321
PMCPMC12853163

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.