Evidence map›Paper›PMID 41607143›Full record

ArticleAnnals of dermatology2026

The Evolving Global Burden of Alopecia Areata in Young Adults: High-Income Nations Bear the Greatest Impact.

Yuan Ma, Yuanchen Zhang, Shuai Dong, Yan Mu

Abstract read
In one paragraph

Article in Annals of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuan MaDepartment of Dermatology, The Second Hospital of Jilin University, Changchun, China.ORCID https://orcid.org/0009-0002-0324-2489
Yuanchen ZhangDepartment of Dermatology, The Second Hospital of Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-7131-503X
Shuai DongDepartment of Dermatology, The Second Hospital of Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-7728-4537
Yan MuDepartment of Dermatology, The Second Hospital of Jilin University, Changchun, China. muyan_20031017@jlu.edu.cn.ORCID https://orcid.org/0000-0002-9152-6301

Funding

Jilin Province health science and technology ability improvement project JYTJF2022037Natural Science Foundation of Jilin Province YDZJ202301ZYTS072
6 · The paper itself

Abstract

backgroundThis study quantifies the global burden of alopecia areata (AA) in young adults (15-49 years) from 1990 to 2021 using data from the Global Burden of Disease 2021 study.

objectiveTo analyze trends in AA incidence and disability-adjusted life years (DALYs) across demographic and geographic strata.

methodsWe evaluated age-standardized incidence rates (ASIRs) and age-standardized DALYs rates, stratified by sex, age, and Socio-demographic Index (SDI). Estimated annual percentage changes (EAPCs) were calculated to assess trends.

resultsGlobal ASIR (EAPC, -0.20) and DALY rates (EAPC, -0.19) for AA declined 1990-2021, with larger declines in women, peak rates in 30-34-year-olds, and most prominent declines in high-SDI regions. High-SDI regions accounted for 42% of global DALYs (18% of the population). East Asia (ASIR EAPC, 0.02) and Oman (ASIR EAPC, 0.46) had rising incidence; East Asia (DALY EAPC, 0.04) and Guatemala (DALY EAPC, 0.48) had rising burden. SDI correlated positively with AA burden (ASIR: r=0.68,

conclusionSignificant disparities exist in AA burden, with higher rates in females and a peak in young adulthood. The strong positive correlation with SDI highlights the disproportionate impact of AA on high-income nations.

Indexed as

Age-standardized incidence rateAlopecia areataDisability-adjusted life-yearIncidenceThe GBD 2021

Identifiers

PMID41607143
PMCPMC12868752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.