Evidence map›Paper›PMID 41607102›Full record

SynthesisJournal of surgical oncology2026

Cervical Cancer Prevention and Treatment Disparities Among Native Hawaiian and Pacific Islanders: A Systematic Review and Meta-Analysis.

Antoinette T Nguyen, Emily D Duckworth, Rena A Li, Tarifa H Adam, Robert D Galiano

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antoinette T NguyenUniversity of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
Emily D DuckworthUniversity of South Carolina School of Medicine Greenville, Greenville, South Carolina, USA.
Rena A LiNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Tarifa H AdamNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Robert D GalianoNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-9552-6483

Funding

Crown Family Philanthropies
6 · The paper itself

Abstract

backgroundNative Hawaiian and Pacific Islander (NHPI) populations face significant disparities in cervical cancer prevention and treatment. This systematic review and meta-analysis examines cervical cancer prevention metrics, treatment disparities, and effective interventions among NHPI populations.

methodsFollowing PRISMA guidelines, we systematically searched PubMed, Scopus, and Embase for studies published between 2000 and 2024 that reported cervical cancer prevention metrics in NHPI populations. Eligible studies included quantitative and qualitative designs with NHPI-specific or disaggregated data. Pap testing and HPV vaccination rates were pooled using a random-effects meta-analysis. Narrative synthesis summarized findings from studies unsuitable for meta-analysis.

resultsA total of 27 studies were included. The pooled Pap testing rate was 62% (95% CI: 46%-75%), with substantial heterogeneity (I² = 98.7%). The pooled HPV vaccine initiation rate was 25% (95% CI: 16%-37%; I² = 84.3%). Barriers included limited healthcare access, lack of physician recommendations, cultural stigma, and geographic isolation. Effective interventions, such as culturally tailored educational materials and community-based participatory approaches, demonstrated improved screening and vaccination rates. NHPI patients were less likely to receive timely and guideline-concordant cervical cancer treatment and had higher rates of late-stage diagnoses and mortality.

conclusionsNHPI populations face persistent cervical cancer prevention and treatment disparities. Culturally tailored interventions and policies addressing systemic barriers are critical to reducing these inequities. Future research should focus on longitudinal studies and scalable interventions to improve outcomes in NHPI communities.

Indexed as

Healthcare DisparitiesNative Hawaiian or Pacific IslanderUterine Cervical NeoplasmsEarly Detection of CancerFemaleHawaiiHuman Papillomavirus VirusesHumansPapillomavirus InfectionsPapillomavirus VaccinesPapillomavirus Vaccinescervical cancerhealth disparitiesHPV vaccinationnative HawaiianPacific IslanderPap testing

Identifiers

PMID41607102
PMCPMC13058393

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.