ArticleJournal of medical primatology2026
Comparison of Laser Doppler Flowmetry With Contrast-Enhanced Ultrasound to Approximate Placental Microvascular Blood Flow in the African Green Monkey (Chlorocebus aethiops sabaeus).
Article in Journal of medical primatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Contrast enhanced ultrasound and laser doppler flowmetry capture distinct aspects of tissue microvascular perfusion in nonhuman primates.Physiological reports · 2026Article
- Comparison of Laser Doppler Flowmetry With Contrast-Enhanced Ultrasound to Approximate Placental Microvascular Blood Flow in the African Green Monkey (Chlorocebus aethiops sabaeus).Journal of medical primatology · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe ability to study in vivo microvascular flow within the placenta is limited. We sought to compare two techniques for evaluation of placental perfusion in a translational nonhuman primate model.
methodsWe measured placental microvascular perfusion in six pregnant African green monkeys (Chlorocebus aethiops sabaeus) using both Laser Doppler Flowmetry (LDF) and contrast-enhanced ultrasound (CEUS) in 2-4 discrete placental locations per animal at early- (EG), mid- (MG), and/or late-gestation (LG). We assessed correlation between matched LDF and CEUS, with the hypothesis that we would observe concordance between these two measures of relative perfusion.
resultsUsing 35 total paired measurements (13 EG, n = 4; 12 MG, n = 4; 10 LG, n = 5), we found no correlation between LDF microvascular perfusion and CEUS microvascular flux rate (Pearson r = -0.2026, R
conclusionLDF and CEUS produce discordant results with respect to placental perfusion. LDF is ill-suited to a heterogeneous organ such as the placenta.
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