Evidence map›Paper›PMID 41606832›Full record

ArticleAutophagy2026

Deubiquitinase USP15 restricts LC3-dependent targeting of

Kathryn C Rahlwes, Priscila C Campos, Beatriz R S Dias, Paola K Párraga Solórzano, Michael U Shiloh

Abstract read
In one paragraph

Article in Autophagy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kathryn C RahlwesDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-8101-5604
Priscila C CamposDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-1789-3290
Beatriz R S DiasDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-7433-3869
Paola K Párraga SolórzanoDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-0710-5414
Michael U ShilohDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-4329-2253

Funding

RP5: Chemical proteomic discovery of small-molecule probes for autophagy proteinsU19AI142784 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI CRAVATT, BENJAMIN F · 2019 to 2023
$36.9M
TRAINING PROGRAM IN LUNG BIOLOGY AND DISEASET32HL098040 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAUL, PHILIP W, TERADA, LANCE S · 2009 to 2024
$4.6M
Role of Ubiquitin Ligases and Deubiquitinases in Host Defense against Mycobacterium tuberculosisR01AI187291 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SHILOH, MICHAEL · 2025 to 2025
$3.3M
Spinning Disk Confocal for UT SouthwesternS10OD028630 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI LUBY-PHELPS, KATHERINE J · 2020 to 2020
$600k
NHLBI NIH HHS T32 HL098040NIAID NIH HHS R01 AI187291NIAID NIH HHS U19 AI142784NIH HHS S10 OD028630
6 · The paper itself

Abstract

Macroautophagy/autophagy enables macrophages to degrade intracellular

Indexed as

Microtubule-Associated ProteinsMycobacterium tuberculosisUbiquitin-Specific ProteasesAnimalsAutophagyHost-Directed TherapyHumansMacrophagesMiceUbiquitinationMicrotubule-Associated ProteinsUbiquitin-Specific ProteasesUSP15 protein, humanDeubiquitinasehost-directed therapyinnate immunitytuberculosisubiquitinxenophagy

Identifiers

PMID41606832
PMCPMC12888086

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.