ArticleSystematic reviews2026
Association between adverse childhood experiences and asthma: a protocol for meta-analysis.
Article in Systematic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAdverse childhood experiences (ACEs) are associated with the development of asthma, but the link between the two remains controversial currently. This protocol describes a systematic review and meta-analysis to evaluate the association between different ACEs and asthma.
methodsWe will conduct a comprehensive search across PubMed, Embase, Cochrane Library, and Web of Science to identify research pertaining to the correlation between ACEs and asthma, spanning from the inception of these databases to April 30, 2025. The information primarily will encompass fundamental study attributes (such as lead author, publication year, geographical location, and study design) and essential demographic details (including sample size, gender distribution, and average age) of the study populations. The primary focus is on examining the relationship between ACEs and asthma, with the quality assessment of included case-control or cohort studies being conducted using the Newcastle-Ottawa Scale (NOS). The processes of literature screening, data extraction, and bias evaluation will be independently carried out in duplicate by two investigators. In instances where meta-analysis is not applicable, we will employ optimal methods for integrating evidence descriptively. DISCUSSION: This protocol will use meta-analysis to prove the relationship between different types of ACEs and asthma, hoping to improve the quality of life of children with ACEs and reduce the incidence of asthma. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42024544950.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.