ReviewEcho research and practice2026
Accuracy of 3-dimensional echocardiography in measuring right ventricular volumes and ejection fraction: a systematic review and meta-analysis.
Review in Echo research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
BACKGROUND AND
aimsThe complex architecture of the right ventricle presents a significant challenge in determining its functional status. Three-dimensional echocardiography (3DE) is growing in prevalence as a faster and more convenient tool to evaluate Right Ventricular (RV) function. However, its accuracy and concordance with cardiac magnetic resonance imaging (CMR) is yet to be determined. In this study, we conducted a comprehensive systematic review and meta-analysis to evaluate the agreement of 3DE to CMR for RV functional assessment.
methodsWe conducted a systematic literature review of PubMed, Embase, and the Cochrane Library through to December 2024. Studies were included if they directly compared 3DE and CMR measurements of RV function and volumes. Data synthesis was carried out with RevMan Web using a random-effects model.
resultsSeventy-five studies were included in the analysis. 3DE systematically underestimated RV volumes compared to CMR, with significant differences for end-diastolic volume (SMD = −0.43, 95% CI: −0.55, −0.30) and end-systolic volume (SMD: −0.27, 95% CI: −0.39, −0.16). However, for RV ejection fraction, 3DE showed minimal underestimation (MD: −0.92%, 95% CI: −2.20, 0.36) with no statistically significant difference (p: 0.16).
conclusionThese findings support the potential clinical utility of 3DE for RV ejection fraction assessment while highlighting the continued importance of CMR for precise volume measurements.
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