Evidence map›Paper›PMID 41606660›Full record

ArticleHead & face medicine2026

Long-term stability of ocular function after alloplastic computer-aided design/computer-aided manufacturing reconstruction of posttraumatic orbital defects: a retrospective cohort study.

S Skade, M L Linderkamp, F Lentge, P Korn, P Jehn, N C Gellrich, K Hufendiek, R Zimmerer, M T Neuhaus

Abstract read
In one paragraph

Article in Head & face medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

S SkadeDepartment of Oral and Maxillofacial Surgery, Hannover Medical School, 30625, Hannover, Germany. Skade.Sandra@mh-hannover.de.
M L LinderkampDepartment of Oral and Maxillofacial Surgery, Hannover Medical School, 30625, Hannover, Germany.
F LentgeDepartment of Oral and Maxillofacial Surgery, Hannover Medical School, 30625, Hannover, Germany.
P KornDepartment of Oral and Maxillofacial Surgery, Hannover Medical School, 30625, Hannover, Germany.
P JehnDepartment of Oral and Maxillofacial Surgery, Hannover Medical School, 30625, Hannover, Germany.
N C GellrichDepartment of Oral and Maxillofacial Surgery, Hannover Medical School, 30625, Hannover, Germany.
K HufendiekDepartment of Ophthalmology, Hannover Medical School, 30625, Hannover, Germany.
R ZimmererDepartment of Oral and Maxillofacial Surgery, University Hospital Tuebingen, 72076, Tuebingen, Germany.
M T NeuhausDepartment of Oral and Maxillofacial Surgery, Hannover Medical School, 30625, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated the long-term stability of ocular function and eyeball position after posttraumatic orbital reconstruction of patient-specific implants using alloplastic computer-aided design/computer-aided manufacturing (CAD/CAM). In this study, we evaluated the extent to which precise anatomical reconstruction contributes to stable functional and aesthetic outcomes over time.

methodsBetween 2010 and 2018, we retrospectively analyzed 69 patients who underwent orbital floor and medial wall reconstruction. The patients were classified into two groups following the implant type: CAD/CAM-manufactured titanium implants and standard CAD-based titanium implants. Long-term follow-up (LTFU) assessments included globe positioning, diplopia, motility, visual acuity, and intraocular pressure. The differences between the two groups were determined using statistical analyses.

resultsDeviations in the sagittal and vertical globe positions persisted after a median follow-up of 56 months in both groups, with no significant differences. Vertical globe deviation is significantly associated with diplopia. Patients with CAD-based implants showed a higher tendency for motility restriction and lower visual acuity than those with CAD/CAM implants. Intraocular pressure was significantly lower in the affected eyes in both groups.

conclusionCAD/CAM-designed implants provide improved anatomical reconstruction; however, they do not significantly improve long-term globe positioning than CAD-based implants. However, they may also contribute to improved motility and visual outcomes. A close interdisciplinary approach involving ophthalmologists is important for optimizing treatment planning and postoperative assessments.

Indexed as

Computer-Aided DesignOrbitOrbital FracturesOrbital ImplantsPlastic Surgery ProceduresAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedProsthesis DesignRetrospective StudiesTitaniumTreatment OutcomeVisual AcuityTitaniumComputer-aided design/Computer-aided manufacturingDiplopiaEyeball positionOcular motilityOrbital floor reconstructionTitanium implantVisual acuity

Identifiers

PMID41606660
PMCPMC12930717

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.