Evidence map›Paper›PMID 41606593›Full record

ReviewMicrobial cell factories2026

Staphylococcus aureus's golden-yellow pigment staphyloxanthin: production enhancement, analytical characterization, and biological attributes.

Ahmed M Nosair, Amal M Abo-Kamar, Lamiaa A Al-Madboly, Mahmoud H Farghali, Ahmed A Abdelaziz

Abstract readReview
In one paragraph

Review in Microbial cell factories, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed M NosairDepartment of Microbiology and Immunology, Faculty of Pharmacy, Tanta University, Tanta, Egypt. ahmed.nosir@pharm.tanta.edu.eg.
Amal M Abo-KamarDepartment of Microbiology and Immunology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
Lamiaa A Al-MadbolyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
Mahmoud H FarghaliDepartment of Microbiology and Immunology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.ORCID http://orcid.org/0000-0001-5954-7842
Ahmed A AbdelazizDepartment of Microbiology and Immunology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphyloxanthin (STX), an apocarotenoid golden yellow pigment produced by Staphylococcus aureus isolates, is endowed with potent antioxidant capacity. It plays a crucial role in combating reactive oxygen species (ROS), exhibiting considerable application prospects. This review provides a comprehensive overview of the biosynthetic pathway and various approaches for STX bioproduction in S. aureus. Moreover, this review focuses on advancements in biotechnology for enhancing the yield of STX in S. aureus, including mutagenesis breeding, metabolic engineering, transcriptional regulation, and the optimization of fermentation conditions. This review addresses the extraction process, purification, and analytical characterization of STX pigment. Additionally, this review highlights the diverse applications of STX in healthcare settings as an antibacterial, antifungal, antiparasitic, antioxidant, anticancer, and DNA damage protection agent. To the best of our knowledge, this is the first review reporting the biotechnological aspects of STX from S. aureus as a natural biotechnologically valued product.

Indexed as

Pigments, BiologicalStaphylococcus aureusXanthophyllsBiosynthetic PathwaysFermentationMetabolic EngineeringPigments, BiologicalstaphyloxanthinXanthophyllsBiological activitiesBioproductionExtractionPurificationStaphylococcus aureusStaphyloxanthin

Identifiers

PMID41606593
PMCPMC12924280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.